Evidence map›Paper›PMID 27118489›Full record

ArticleMucosal immunology2017

Gut commensal Bacteroides acidifaciens prevents obesity and improves insulin sensitivity in mice.

J-Y Yang, Y-S Lee, Y Kim, S-H Lee, S Ryu, S Fukuda, K Hase, C-S Yang, H S Lim, M-S Kim and 5 more

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Mucosal immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 229 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
229citing papers in PubMed, 4 pooled it
11.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

229 citing papers in PubMed, 4 syntheses or guidelines pooled it, 432 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
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  7. Article
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  11. Review
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  14. The Safety ofViruses · 2026
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  15. Review
  16. Gut Microbiota-Mediated Mechanisms of Traditional Chinese Medicine in Obesity Management.Diabetes, metabolic syndrome and obesity : targets and therapy · 2026
    Review
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  18. Gut microbes · 2025
    Article
  19. Review
  20. Article

169 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 2 countries.

J-Y YangMucosal Immunology Laboratory, Department of Convergence Medicine, University of Ulsan College of Medicine/Asan Medical Center, Seoul, Korea.
Y-S LeeMucosal Immunology Laboratory, Department of Convergence Medicine, University of Ulsan College of Medicine/Asan Medical Center, Seoul, Korea.
Y KimMucosal Immunology Laboratory, Department of Convergence Medicine, University of Ulsan College of Medicine/Asan Medical Center, Seoul, Korea.
S-H LeeMucosal Immunology Laboratory, Department of Convergence Medicine, University of Ulsan College of Medicine/Asan Medical Center, Seoul, Korea.
S RyuDepartment of Agricultural Biotechnology, Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul, Korea.
S FukudaInstitute for Advanced Biosciences, Keio University, Yamagata, Japan.
K HaseDepartment of Biochemistry, Graduate School of Pharmacological Science, Keio University, Tokyo, Japan.
C-S YangDepartment of Molecular and Life Science, College of Science and Technology, Hanyang University, Ansan, Korea.
H S LimDivision of Endocrinology and Metabolism, Department of Internal Medicine, University of Ulsan College of Medicine/Asan Medical Center, Seoul, Korea.
M-S KimDivision of Endocrinology and Metabolism, Department of Internal Medicine, University of Ulsan College of Medicine/Asan Medical Center, Seoul, Korea.
H-M KimDepartment of Internal Medicine, Yonsei University, Wonju College of Medicine, Wonju, Korea.
S-H AhnLaboratory of Pharmaceutics, College of Pharmacy, Kangwon National University, Chuncheon, Korea.
B-E KwonLaboratory of Microbiology and Immunology, College of Pharmacy, Kangwon National University, Chuncheon, Korea.
H-J KoLaboratory of Microbiology and Immunology, College of Pharmacy, Kangwon National University, Chuncheon, Korea.
M-N KweonMucosal Immunology Laboratory, Department of Convergence Medicine, University of Ulsan College of Medicine/Asan Medical Center, Seoul, Korea.
Ulsan College · KRKangwon National University · KRKeio University · JPHanyang University · KRSeoul National University · KRYonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In humans, the composition of gut commensal bacteria is closely correlated with obesity. The bacteria modulate metabolites and influence host immunity. In this study, we attempted to determine whether there is a direct correlation between specific commensal bacteria and host metabolism. As mice aged, we found significantly reduced body weight and fat mass in Atg7

Indexed as

Adipose TissueAnimalsAutophagy-Related Protein 7BacteroidesCells, CulturedDipeptidyl Peptidase 4FecesGastrointestinal MicrobiomeGene Expression RegulationGlucagon-Like Peptide 1HumansInsulinInsulin ResistanceIntestinesMiceMice, Inbred C57BLAtg7 protein, mouseAutophagy-Related Protein 7Dipeptidyl Peptidase 4Glucagon-Like Peptide 1InsulinPPAR alpha

Identifiers

PMID27118489
OpenAlexW2343917624

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.