ArticleScientific reports2016
Transcriptome analysis of interactions between silkworm and cytoplasmic polyhedrosis virus.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 41 citations in OpenAlex.
- IRES-like element-mediated translation of vsp1S4(-) suppresses BmCPV replication via RNAi antagonism.PLoS pathogens · 2026Article
- Insect cypoviruses: advances in structural characterization, evolutionary genomics, and host interaction dynamics.Archives of virology · 2026Review
- Genome-scale DNA methylome and transcriptome profiling of midgut of Bombyx mori infected with BmCPV.Scientific data · 2026Article
- DsRNA as pathogen-associated molecular pattern in innate immunity and multiple functions of the RNAi machinery complicate the use of RNAi in pest control.Frontiers in insect science · 2025Review
- Identification of Key Genes Involved in Resistance to Early Stage of BmNPV Infection in Silkworms.Viruses · 2022Article
- Carbohydrate metabolism is a determinant for the host specificity of baculovirus infections.iScience · 2022Article
- BmCPV-Derived Circular DNA vcDNA-S7 Mediated byFrontiers in immunology · 2022Article
- Transcriptional responses of Daphnis nerii larval midgut to oral infection by Daphnis nerii cypovirus-23.Virology journal · 2021Article
- Insights Into the Antiviral Pathways of the SilkwormFrontiers in immunology · 2021Review
- Identification of Membrane-Bound Lytic Murein Transglycosylase A (MltA) as a Growth Factor forFrontiers in cellular and infection microbiology · 2020Article
- Antimicrobial Peptides as Potential Antiviral Factors in Insect Antiviral Immune Response.Frontiers in immunology · 2020Review
- Adenosine Receptor Modulates Permissiveness of Baculovirus (Budded Virus) Infection via Regulation of Energy Metabolism inFrontiers in immunology · 2020Article
- Distinct Functions ofFrontiers in immunology · 2019Article
- RNA Interference in Insects: Protecting Beneficials and Controlling Pests.Frontiers in physiology · 2018Review
- Symbiosis with Francisella tularensis provides resistance to pathogens in the silkworm.Scientific reports · 2016Article
- Selection of reference genes for analysis of stress-responsive genes after challenge with viruses and temperature changes in the silkworm Bombyx mori.Molecular genetics and genomics : MGG · 2016Article
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bombyx mori cytoplasmic polyhedrosis virus (BmCPV) specifically infects silkworm midgut (MG) and multiplication occurs mainly in posterior midgut (PM). In this study, MG and fat body (FB) were extracted at 0, 3, 24, and 72 h after BmCPV infection. The total sequence reads of each sample were more than 1510000, and the mapping ratio exceeded 95.3%. Upregulated transcripts increased in MG during the infection process. Gene ontology (GO) categories showed that antioxidants were all upregulated in FB but not in MG. BGI001299, BGI014434, BGI012068, and BGI009201 were MG-specific genes with transmembrane transport function, the expression of which were induced by BmCPV. BGI001299, BGI014434, and BGI012068 expressed in entire MG and may be involved in BmCPV invasion. BGI009201 expressed only in PM and may be necessary for BmCPV proliferation. BmPGRP-S2 and BGI012452 (a putative serine protease) were induced by BmCPV and may be involved in immune defense against BmCPV. The expression level of BmCPV S1, S2, S3, S6, and S7 was high and there was no expression of S9 in MG 72 h, implying that the expression time of structural protein coding genes is earlier. These results provide insights into the mechanism of BmCPV infection and host defense.
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