Evidence map›Paper›PMID 27118285›Full record

ArticleBMJ open2016

Association between alcohol drinking behaviour and cognitive function: results from a nationwide longitudinal study of South Korea.

Sujin Kim, Yongjoo Kim, Sang Min Park

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 38 citations in OpenAlex.

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  14. Cognitive Decline and Recovery in Alcohol Abuse.Journal of molecular neuroscience : MN · 2016
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Sujin KimTakemi Program in International Health, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA.
Yongjoo KimDepartment of Social and Behavioral Sciences, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA.
Sang Min ParkTakemi Program in International Health, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA Department of Family Medicine & Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, South Korea.
Harvard Global Health Institute · USHarvard University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis research intends to determine how drinking behaviour, such as episodic heavy drinking, is related to cognitive performance in middle-aged and old-aged people in South Korea.

methodsA cohort data of 5157 adults, age 45 years or older, with normal cognitive function (the Korean version of the Mini-mental state examination (K-MMSE) ≥24) at baseline (2006), was derived from the Korean Longitudinal Study of Aging. Alcohol drinking behaviour was assessed using the CAGE (Cut down, Annoyed, Guilty, Eye-opener) questionnaire. The relationships between baseline drinking behaviour (in 2006) to the extent of cognitive decline (between 2006 and 2012) and development of cognitive impairment (in 2012) were assessed.

resultsIndividuals with problematic drinking behaviour at baseline experienced a faster decline in cognitive function than those with non-problematic drinking (p<0.05) during 6 years of follow-up, especially among those with relatively lownormal K-MMSE score (24-26) at baseline (p<0.05). Problematic alcohol drinking behaviour was also significantly associated with onset of severe cognitive impairment (SCI) (K-MMSE score ≤17) among those with relatively low-normal K-MMSE score (adjusted OR (aOR)=3.76, 95% CI 1.46 to 9.67). In addition, abstinence, compared with non-problematic drinking, was related to higher risk for developing SCI among men (aOR=1.62, 95% CI 1.09 to 2.39).

conclusionsOur results suggest that those with problematic alcohol drinking behaviour could be at an increased risk of cognitive impairment/decline. While further research will provide stronger evidence, intervention targeting alcohol abuse may play a role in prevention of cognitive impairment.

Indexed as

AgedAged, 80 and overAge DistributionAlcohol DrinkingCognitionCognitive DysfunctionFemaleHumansLinear ModelsLogistic ModelsLongitudinal StudiesMaleMiddle AgedNeuropsychological TestsPsychiatric Status Rating ScalesRepublic of KoreaEPIDEMIOLOGYPUBLIC HEALTH

Identifiers

PMID27118285
PMCPMC4854012
OpenAlexW2343313012

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.