Evidence map›Paper›PMID 27117689›Full record

ArticleSurgery today2017

Postoperative complications following aggressive repeat hepatectomy for colorectal liver metastasis have adverse oncological outcomes.

Yasuyuki Fukami, Yuji Kaneoka, Atsuyuki Maeda, Yuichi Takayama, Shunsuke Onoe

Abstract read
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In one paragraph

Article in Surgery today, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. HEPATECTOMIES: INDICATIONS AND RESULTS FROM A REFERENCE HOSPITAL IN THE BRAZILIAN AMAZON.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2024
    Article
  3. Article
  4. Article
  5. Limited Effect of Perioperative Systemic Therapy in Patients Selected for Repeat Local Treatment of Recurrent Colorectal Cancer Liver Metastases.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2022
    Article
  6. RE-HEPATECTOMY MEANS MORE MORBIDITY? A MULTICENTRIC ANALYSIS.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yasuyuki FukamiDepartment of Surgery, Ogaki Municipal Hospital, 4-86 Minaminokawa-cho, 503-8502, Ogaki, Gifu, Japan. yasuyuki490225@yahoo.co.jp.
Yuji KaneokaDepartment of Surgery, Ogaki Municipal Hospital, 4-86 Minaminokawa-cho, 503-8502, Ogaki, Gifu, Japan.
Atsuyuki MaedaDepartment of Surgery, Ogaki Municipal Hospital, 4-86 Minaminokawa-cho, 503-8502, Ogaki, Gifu, Japan.
Yuichi TakayamaDepartment of Surgery, Ogaki Municipal Hospital, 4-86 Minaminokawa-cho, 503-8502, Ogaki, Gifu, Japan.
Shunsuke OnoeDepartment of Surgery, Ogaki Municipal Hospital, 4-86 Minaminokawa-cho, 503-8502, Ogaki, Gifu, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposesRepeat hepatectomy remains the only curative treatment for recurrent colorectal liver metastasis (CLM) after primary hepatectomy. However, the repeat resection rate is still low, and there is insufficient data on the outcomes after repeat hepatectomy. The aim of this study was to investigate the feasibility and prognostic benefit of aggressive repeat hepatectomy for recurrent CLM.

methodsData were reviewed from 282 consecutive patients who underwent primary curative hepatectomy for CLM between January 1994 and March 2015. The short- and long-term outcomes were analyzed.

resultsOne hundred ninety-three patients (68 %) developed recurrence, and repeat hepatectomy was conducted in 62 patients. Overall, 62 s, 11 third, 4 fourth, and 1 fifth hepatectomies were performed. The postoperative morbidity and mortality rates were low (11.5 and 1.3 %, respectively). The overall survival rates at 3 and 5 years after primary hepatectomy for CLM in the repeat hepatectomy group were 79.5 and 57.4 %, respectively. A multivariate analysis indicated that postoperative complications were independently associated with overall survival after repeat hepatectomy.

conclusionsRepeat hepatectomy for CLM is feasible, with acceptable rates of perioperative morbidity and mortality, and the potential for long-term survival. However, postoperative complications following aggressive repeat hepatectomy for CLM are associated with adverse oncological outcomes.

Indexed as

AgedColorectal NeoplasmsFeasibility StudiesFemaleHepatectomyHumansLiver NeoplasmsMaleMiddle AgedMorbidityMultivariate AnalysisNeoplasm Recurrence, LocalPostoperative ComplicationsReoperationSurvival RateTime FactorsColorectal liver metastasesHepatectomyPostoperative complicationRecurrenceRepeat resection

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.