Evidence map›Paper›PMID 27117317›Full record

ArticleThe Korean journal of internal medicine2016

Opportunistic diseases among HIV-infected patients: a multicenter-nationwide Korean HIV/AIDS cohort study, 2006 to 2013.

Youn Jeong Kim, Jun Hee Woo, Min Ja Kim, Dae Won Park, Joon-Young Song, Shin Woo Kim, Jun Yong Choi, June Myung Kim, Sang Hoon Han, Jin-Soo Lee and 6 more

2 registry-linked trialsOpen access · goldAbstract readMulticenter Study
In one paragraph

Article in The Korean journal of internal medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05153005 unknown statusnot on this mapstarted 2021, after this paper: background citation

Comprehensive Diagnosis and Treatment Strategy for Opportunistic Fungal Infections in AIDS Patients

TypeobservationalSponsorGuangzhou 8th People's HospitalRan2021 to 2023Enrolled600ConditionsOpportunistic Fungal InfectionsArmsexamination methods
NCT05898464 phase4completednot on this mapstarted 2023, after this paper: background citation

Immunogenicity and Safety of Recombinant Zoster Vaccine in People Living With HIV

TypeinterventionalSponsorSeoul National University HospitalRan2023 to 2026Enrolled71ConditionsVaccination, Infection, Vaccine Adverse ReactionArmsRecombinant zoster vaccination
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 57 citations in OpenAlex.

  1. Pooled it
  2. Pathogens and global health · 2020
    Pooled it
  3. Article
  4. Evolving Disease Spectrum and Characteristics of People with HIV in Eastern China: A 12-Year Study.Mediterranean journal of hematology and infectious diseases · 2025
    Article
  5. Article
  6. Article
  7. Spectrum and mortality of opportunistic infections among HIV/AIDS patients in southwestern China.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Effects of infections on the pathogenesis of cancer.The Indian journal of medical research · 2021
    Review
  16. Observational
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 9 institutions in 1 country.

Youn Jeong KimDivision of Infectious Disease, Department of Internal Medicine, College of Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea.
Jun Hee WooDepartment of Infectious Disease, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Min Ja KimDepartment of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
Dae Won ParkDepartment of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
Joon-Young SongDepartment of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
Shin Woo KimDepartment of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Korea.
Jun Yong ChoiDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
June Myung KimDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Sang Hoon HanDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Jin-Soo LeeDepartment of Internal Medicine, Inha University School of Medicine, Incheon, Korea.
Bo Youl ChoiDepartment of Preventive Medicine, Hanyang University College of Medicine, Seoul, Korea.
Joo Shil LeeKorea Centers for Disease Control and Prevention, Cheongju, Korea.
Sung-Soon KimKorea Centers for Disease Control and Prevention, Cheongju, Korea.
Mee-Kyung KeeKorea Centers for Disease Control and Prevention, Cheongju, Korea.
Moon Won KangDivision of Infectious Disease, Department of Internal Medicine, College of Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea.
Sang Il KimDivision of Infectious Disease, Department of Internal Medicine, College of Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea.
Korea University · KRYonsei University · KRKorea Center for Disease Control and Prevention · KRKorea Disease Control and Prevention Agency · KRSeoul St. Mary's Hospital · KRCatholic University of Korea · KRHanyang University · KRInha University · KRUniversity of Ulsan · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsThe frequencies of opportunistic diseases (ODs) vary across countries based on genetic, environmental, and social differences. The Korean HIV/AIDS cohort study was initiated in 2006 to promote research on human immunodeficiency virus (HIV) infection in Korea, and to provide a logistical network to support multicenter projects on epidemiological, clinical, and laboratory aspects of HIV infection. This study evaluated the prevalence of ODs among HIV-infected patients in the era of highly active antiretroviral therapy, and the risk factors associated with ODs.

methodsThe study enrolled 1,086 HIV-infected patients from 19 hospitals. This study examined the baseline data of the HIV/AIDS Korean cohort study at the time of enrollment from December 2006 to July 2013.

resultsCandidiasis was the most prevalent opportunistic infection (n = 176, 16.2%), followed by Mycobacterium tuberculosis infection (n = 120, 10.9%), Pneumocystis jirovecii pneumonia (n = 121, 11.0%), cytomegalovirus infection (n = 52, 4.7%), and herpes zoster (n = 44, 4.0%). The prevalence rates of Kaposi's sarcoma (n = 8, 0.7%) and toxoplasmosis (n = 4, 0.4%) were very low compared with other countries. The risk factors for ODs were a low CD4 T cell count at the time of HIV diagnosis (odds ratio [OR], 1.01; p < 0.01), current smoking (OR, 2.27; p = 0.01), current alcohol use (OR, 2.57; p = 0.04), and a history of tuberculosis (OR, 5.23; p < 0.01).

conclusionsUsing recent Korean nationwide data, this study demonstrated that an important predictor of ODs was a low CD4 T cell count at the time of HIV diagnosis. Tuberculosis remains one of the most important ODs in HIV-infected patients in Korea.

Indexed as

AdultAIDS-Related Opportunistic InfectionsAntiretroviral Therapy, Highly ActiveCohort StudiesFemaleHIV InfectionsHumansMaleMiddle AgedPrevalenceRepublic of KoreaRisk FactorsAIDS-related opportunistic infectionsHIVKoreaTuberculosis

Identifiers

PMID27117317
PMCPMC5016273
OpenAlexW2342777015

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.