Evidence map›Paper›PMID 27117316›Full record

ReviewThe Korean journal of internal medicine2016

Vitamin D and its effects on cardiovascular diseases: a comprehensive review.

Nonanzit Pérez-Hernández, Gad Aptilon-Duque, María Cristina Nostroza-Hernández, Gilberto Vargas-Alarcón, José Manuel Rodríguez-Pérez, Ruben Blachman-Braun

Open access · goldAbstract readReview
In one paragraph

Review in The Korean journal of internal medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Review
  5. Article
  6. Review
  7. Understanding the Role of Vitamin D in Heart Failure.Reviews in cardiovascular medicine · 2023
    Review
  8. Review
  9. Article
  10. Review
  11. Disease markers · 2021
    Article
  12. Article
  13. Article
  14. Review
  15. Vitamin D and calcium kidney stones: a review and a proposal.International urology and nephrology · 2019
    Review
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Nonanzit Pérez-HernándezDepartment of Molecular Biology, National Institute of Cardiology "Ignacio Chavez", Mexico City, Mexico.
Gad Aptilon-DuqueDepartment of Molecular Biology, National Institute of Cardiology "Ignacio Chavez", Mexico City, Mexico.
María Cristina Nostroza-HernándezDepartment of Molecular Biology, National Institute of Cardiology "Ignacio Chavez", Mexico City, Mexico.
Gilberto Vargas-AlarcónDepartment of Molecular Biology, National Institute of Cardiology "Ignacio Chavez", Mexico City, Mexico.
José Manuel Rodríguez-PérezDepartment of Molecular Biology, National Institute of Cardiology "Ignacio Chavez", Mexico City, Mexico.
Ruben Blachman-BraunDepartment of Molecular Biology, National Institute of Cardiology "Ignacio Chavez", Mexico City, Mexico.
Instituto Nacional de Cardiología · MXUniversidad Anáhuac · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitamin D is a molecule that is actively involved in multiple metabolic pathways. It is mostly known for its implications related to calcium metabolism. It has also been determined that it actively participates in the cardiovascular system, influencing blood pressure, coronary artery disease and other vascular diseases, such as heart failure and atrial fibrillation. Furthermore, it has been established that this vitamin is extensively involved in the regulation of both the renin angiotensin aldosterone system and the immune system. In this review, we present the different vitamin D metabolic pathways associated with the cardiovascular pathophysiology, and we include studies in animal and human models, as well as some of the controversies found in the literature. This review also incorporates an overview of the implications in the molecular biology and public health fields.

Indexed as

AnimalsCardiovascular DiseasesCardiovascular SystemDietary SupplementsHumansPrognosisRisk FactorsSignal TransductionVitamin DVitamin D DeficiencyVitamin DCardiovascular systemMetabolic networks and pathwaysVitamin D

Identifiers

PMID27117316
PMCPMC5094929
OpenAlexW2345259049

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.