Evidence map›Paper›PMID 27117179›Full record

ReviewSeminars in perinatology2016

What we learned about the role of antenatal magnesium sulfate for the prevention of cerebral palsy.

Dwight J Rouse, Deborah Hirtz, Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network

Abstract readReview
In one paragraph

Review in Seminars in perinatology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. The complex aetiology of cerebral palsy.Nature reviews. Neurology · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Dwight J RouseDepartment of Obstetrics and Gynecology, Warren Alpert Medical School, Brown University, Providence, RI 02905. Electronic address: DRouse@Wihri.org.
Deborah HirtzDepartment of Neurological Sciences and Pediatrics, University of Vermont HSRF 426, 149 Beaumont Avenue, Burlington, VT 05405.
Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network
Brown University · USUniversity of Vermont · US

Funding

NICHD Maternal Fetal Medicine Units NetworkU10HD027869 · NICHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI TITA, ALAN THEVENET N. · 1991 to 2015
$12.8M
NICHD Maternal-Fetal Medicine Units (MFMU) NetworkUG1HD040500 · NICHD · WOMEN AND INFANTS HOSPITAL-RHODE ISLAND · PI DWIGHT J ROUSE · 2016 to 2026
$3.4M
NICHD NIH HHS U10 HD027869NICHD NIH HHS UG1 HD040500
6 · The paper itself

Abstract

Based on the convincing case control study of Nelson and Grether which suggested that the administration of magnesium sulfate to mothers prior to early preterm birth might protect their offspring from cerebral palsy, and a pilot study by John Hauth et al. at the University of Alabama at Birmingham, the Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network, with co-funding from the National Institute of Neurologic Disorders and Stroke embarked on the Beneficial Effects of Antenatal Magnesium (BEAM) Trial in 1997.

Indexed as

Prenatal CareAdultCase-Control StudiesCerebral PalsyDouble-Blind MethodEvidence-Based MedicineFemaleHumansInfant, NewbornInfant, Premature, DiseasesMagnesium SulfateNeuroprotective AgentsPilot ProjectsPregnancyPremature BirthRandomized Controlled Trials as TopicMagnesium SulfateNeuroprotective AgentsCerebral palsyMagnesium sulfate

Identifiers

PMID27117179
PMCPMC6314306
OpenAlexW2339828370

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.