Evidence map›Paper›PMID 27117164›Full record

ReviewCurrent microbiology2016

Molecular Components of the Sporothrix schenckii Complex that Induce Immune Response.

Carlos A Alba-Fierro, Armando Pérez-Torres, Conchita Toriello, Yolanda Romo-Lozano, Everardo López-Romero, Estela Ruiz-Baca

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Sporotrichosis in Mexico.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2021
    Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. The Role of Macrophages in the Host's Defense againstPathogens (Basel, Switzerland) · 2021
    Review
  7. Seroepidemiological survey on sporotrichosis-infection in rural areas of the south of Minas Gerais State, Brazil.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2021
    Article
  8. Review
  9. Skin Mast Cells Contribute toFrontiers in immunology · 2020
    Article
  10. Immunity and Treatment of Sporotrichosis.Journal of fungi (Basel, Switzerland) · 2018
    Review
  11. Immunopathogenesis of Human Sporotrichosis: What We Already Know.Journal of fungi (Basel, Switzerland) · 2018
    Review
  12. Sporotrichin Skin Test for the Diagnosis of Sporotrichosis.Journal of fungi (Basel, Switzerland) · 2018
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Carlos A Alba-FierroFacultad de Ciencias Químicas, Universidad Juárez del Estado de Durango, Av. Veterinaria S/N, 34120, Durango, Dgo., Mexico.
Armando Pérez-TorresDepartamento de Biología Celular y Tisular, Facultad de Medicina, Universidad Nacional Autónoma de México, 04510, Mexico, D.F., Mexico.
Conchita TorielloDepartamento de Microbiología y Parasitología, Facultad de Medicina, Universidad Nacional Autónoma de México, 04510, Mexico, D.F., Mexico.
Yolanda Romo-LozanoDepartamento de Microbiología, Centro de Ciencias Básicas, Universidad Autónoma de Aguascalientes, Av. Universidad # 940, 20131, Aguascalientes, Ags., Mexico.
Everardo López-RomeroDepartamento de Biología, División de Ciencias Naturales y Exactas, Campus Guanajuato, Universidad de Guanajuato, Noria Alta S/N, C.P. 36050, Guanajuato, Gto., Mexico.
Estela Ruiz-BacaFacultad de Ciencias Químicas, Universidad Juárez del Estado de Durango, Av. Veterinaria S/N, 34120, Durango, Dgo., Mexico. erb750@hotmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sporotrichosis is a fungal disease caused by the Sporothrix schenckii complex that includes species such as S. brasiliensis, S. schenckii sensu stricto, S. globosa, S. luriei, S. mexicana, and S. pallida, which exhibit different potentially antigenic molecular components. The immune response of susceptible hosts to control infection and disease caused by these fungi has been little studied. Besides, the fungus-host interaction induces the activation of different types of immune response. This mini-review analyzes and discusses existing reports on the identification and functional characterization of molecules from species of the S. schenckii complex with clinical relevance, and the mechanisms that mediate the type and magnitude of the immune response in experimental models in vivo and in vitro. This knowledge is expected to contribute to the development of protective and therapeutic strategies against sporotrichosis and other mycoses.

Indexed as

AnimalsFungal ProteinsHumansSporothrixSporotrichosisFungal Proteins

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.