ReviewSeminars in immunopathology2016
Role of basophils in protective immunity to parasitic infections.
Review in Seminars in immunopathology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 66 citations in OpenAlex.
- TSLP: contrasting roles in cancer.Frontiers in immunology · 2025Review
- Parasite Infections Influence Immunological Responses But Not Reproductive Success of Male Hellbender Salamanders (Integrative organismal biology (Oxford, England) · 2025Article
- Systemic Immune Modulation by Gastrointestinal Nematodes.Annual review of immunology · 2024Review
- Hematologic Abnormalities and Diseases Associated with Moderate-to-Marked Basophilia in a Large Cohort of Dogs.Veterinary sciences · 2023Article
- Basophil responses in susceptible AKR mice upon infection with the intestinal helminth parasite Trichuris muris.Parasite immunology · 2023Article
- Basophils beyond allergic and parasitic diseases.Frontiers in immunology · 2023Review
- Adjusted association between type 2 immunity and low risk thyroid nodules: a retrospective cohort study.BMC endocrine disorders · 2022Article
- Communication is key: Innate immune cells regulate host protection to helminths.Frontiers in immunology · 2022Review
- IgG Autoantibodies Against IgE from Atopic Dermatitis Can Induce the Release of Cytokines and Proinflammatory Mediators from Basophils and Mast Cells.Frontiers in immunology · 2022Article
- Differential Effects of Alarmins on Human and Mouse Basophils.Frontiers in immunology · 2022Article
- Role of Basophils in a Broad Spectrum of Disorders.Frontiers in immunology · 2022Review
- Malaria-induced bacteremia as a consequence of multiple parasite survival strategies.Current research in microbial sciences · 2021Review
- The role of basophils in acquired protective immunity to tick infestation.Parasite immunology · 2021Review
- Basophils in antihelminth immunity.Seminars in immunology · 2021Review
- Nonlethal Plasmodium yoelii Infection Drives Complex Patterns of Th2-Type Host Immunity and Mast Cell-Dependent Bacteremia.Infection and immunity · 2020Article
- Cytokines and beyond: Regulation of innate immune responses during helminth infection.Cytokine · 2020Review
- Limited role of mast cells during infection with the parasitic nematode Litomosoides sigmodontis.PLoS neglected tropical diseases · 2020Article
- Low host specificity and lack of parasite avoidance by immature ticks in Brazilian birds.Parasitology research · 2020Article
- Is There a Role for Basophils in Cancer?Frontiers in immunology · 2020Review
- Leukocyte Profiles Reflect Geographic Range Limits in a Widespread Neotropical Bat.Integrative and comparative biology · 2019Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Basophils have been recognized as important players for protective immunity against a variety of different endo- and ectoparasites. Although basophils represent a relatively rare and short-lived cell type, they produce large quantities of effector molecules including histamine, cytokines, chemokines, and lipid mediators which promote type 2 immune responses. Basophils can be activated either directly by parasite-derived factors or indirectly by recognition of parasite-derived antigens via IgE bound to its high-affinity receptor FcεRI on the cell surface. Many parasitic infections cause expansion and tissue recruitment of basophils, but the role of basophils for protective immunity remains poorly understood. The development of basophil-deficient mouse models over the past few years makes it possible to study their contributions in various infections. We review here the current knowledge regarding the role of basophils for protective or immunomodulatory functions of basophils mainly during infections of mice with protozoan parasites, helminths, and ectoparasites.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.