ArticleClinical neuroradiology2017
IVIM perfusion fraction is prognostic for survival in brain glioma.
Article in Clinical neuroradiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- Accurate estimation of intravoxel incoherent motion parameters based on implicit neural representation.Medical physics · 2026Article
- Preoperative assessment of intratumor heterogeneity using intravoxel incoherent motion MRI for survival prediction in high-grade gliomas: a feasibility study.BMC medical imaging · 2026Article
- Evaluating the grade and IDH mutation status of gliomas by using intravoxel incoherent motion (IVIM) MRI and DSC perfusion MRI.BMC medical imaging · 2026Article
- A novel MRI diffusion metric 'slow diffusion coefficient' (SDC) for diagnosing isocitrate dehydrogenase (IDH) genotype in diffuse gliomas: initial promising results.BMC medical imaging · 2025Article
- Dynamics of Daily Glioblastoma Evolution During Chemoradiation Therapy on the 0.35T Magnetic Resonance Imaging-Linear Accelerator.International journal of radiation oncology, biology, physics · 2025Article
- Magnetic resonance diffusion-derived vessel density (DDVD) as a valuable tissue perfusion biomarker for isocitrate dehydrogenase genotyping in diffuse gliomas.BMC medical imaging · 2025Article
- Quantitative perfusion and water transport time model from multiJournal of medical imaging (Bellingham, Wash.) · 2023Article
- Biomarkers Predictive of Distant Disease-free Survival Derived from Diffusion-weighted Imaging of Breast Cancer.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2023Article
- Optimizing b-values schemes for diffusion MRI of the brain with segmented Intravoxel Incoherent Motion (IVIM) model.Journal of applied clinical medical physics · 2023Article
- Tumor Progression and Treatment-Related Changes: Radiological Diagnosis Challenges for the Evaluation of Post Treated Glioma.Cancers · 2022Review
- Analysis of DWI in the classification of glioma pathology and its therapeutic application in clinical surgery: a case-control study.Translational cancer research · 2022Article
- Multi-parametric MRI (mpMRI) for treatment response assessment of radiation therapy.Medical physics · 2022Article
- Review
- Intravoxel Incoherent Motion Diffusion-Weighted Imaging and 3D-ASL to Assess the Value of Ki-67 Labeling Index and Grade in Glioma.Scanning · 2022Article
- Evaluation of foot hypoperfusion and estimation of percutaneous transluminal angioplasty outcome in patients with critical limb ischemia using intravoxel incoherent motion microperfusion MRI.The British journal of radiology · 2021Article
- Perfusion-driven Intravoxel Incoherent Motion (IVIM) MRI in Oncology: Applications, Challenges, and Future Trends.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2021Review
- Evaluation of gliomas peritumoral diffusion and prediction of IDH1 mutation by IVIM-DWI.Aging · 2021Article
- Intravoxel incoherent motion (IVIM) modeling of diffusion MRI during chemoradiation predicts therapeutic response in IDH wildtype glioblastoma.Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2021Article
- Application of Intravoxel Incoherent Motion Diffusion-Weighted Imaging in Predicting and Monitoring Early Efficacy of Anti-Angiogenic Therapy in the C6 Glioma Rat Model.Frontiers in oncology · 2021Article
- The diagnostic function of intravoxel incoherent motion for distinguishing between pilocytic astrocytoma and ependymoma.PloS one · 2021Article
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Authors and funding
7 authors.
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Abstract
introductionThe interest in measuring brain perfusion with intravoxel incoherent motion (IVIM) MRI has significantly increased in the last 3 years. Our aim was to evaluate the prognostic value for survival of intravoxel incoherent motion perfusion fraction in patients with gliomas, and compare it to dynamic susceptibility contrast relative cerebral blood volume and apparent diffusion coefficient.
methodsImages were acquired in 27 patients with brain gliomas (16 high grades, 11 low grades), before any relevant treatment. Region of maximal perfusion fraction, maximal relative cerebral blood volume, and minimal apparent diffusion coefficient were obtained. The accuracy of all three methods for 2‑year survival prognosis was compared using the area under the receiver operating characteristic curve and Kaplan-Meier survival curves.
resultsDeath or survival for at least 2 years after imaging could be documented in 22/27 patients. The cutoff values of 0.112 for the perfusion fraction, of 3.01 for the relative cerebral blood volume, and 1033 × 10
conclusionIn this relatively small cohort, maximal IVIM perfusion fraction, similarly to maximal relative cerebral blood volume and minimal apparent diffusion coefficient, was prognostic for survival in patients with gliomas. Maximal IVIM perfusion fraction and minimal apparent diffusion coefficient performed similarly in predicting survival, and both slightly outperformed maximal relative cerebral blood volume.
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