Evidence map›Paper›PMID 27116196›Full record

Trial reportInternational urogynecology journal2016

Mindfulness-based stress reduction as a novel treatment for interstitial cystitis/bladder pain syndrome: a randomized controlled trial.

Gregory Kanter, Yuko M Komesu, Fares Qaedan, Peter C Jeppson, Gena C Dunivan, Sara B Cichowski, Rebecca G Rogers

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in International urogynecology journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04329533 (Effects of a Mobile Meditation App on Stress During COVID-19 Pandemic in Outpatient Obstetrics and Gynecology Patients; a Randomized Controlled Trial), which is not on this map. Cited by 31 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04329533 nacompletednot on this mapstarted 2020, after this paper: background citation

Effects of a Mobile Meditation App on Stress During COVID-19 Pandemic in Outpatient Obstetrics and Gynecology Patients; a Randomized Controlled Trial

TypeinterventionalSponsorUniversity of ArizonaRan2020 to 2020Enrolled101ConditionsPerceived Stress, Anxiety, Sleep DisturbanceArms"Calm" is a mindfulness meditation mobile app
3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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  5. Mindfulness Meditation for Chronic Pain: Systematic Review and Meta-analysis.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gregory KanterDepartment of Obstetrics and Gynecology, MSC 10-5580, 1 University of New Mexico, Albuquerque, NM, 87131-0001, USA.
Yuko M KomesuDepartment of Obstetrics and Gynecology, MSC 10-5580, 1 University of New Mexico, Albuquerque, NM, 87131-0001, USA. ykomesu@salud.unm.edu.
Fares QaedanDepartment of Obstetrics and Gynecology, MSC 10-5580, 1 University of New Mexico, Albuquerque, NM, 87131-0001, USA.
Peter C JeppsonDepartment of Obstetrics and Gynecology, MSC 10-5580, 1 University of New Mexico, Albuquerque, NM, 87131-0001, USA.
Gena C DunivanDepartment of Obstetrics and Gynecology, MSC 10-5580, 1 University of New Mexico, Albuquerque, NM, 87131-0001, USA.
Sara B CichowskiDepartment of Obstetrics and Gynecology, MSC 10-5580, 1 University of New Mexico, Albuquerque, NM, 87131-0001, USA.
Rebecca G RogersDepartment of Obstetrics and Gynecology, MSC 10-5580, 1 University of New Mexico, Albuquerque, NM, 87131-0001, USA.

Funding

UNM HSC Clinical and Translational Science CenterUL1TR001449 · NCATS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI CAMPEN, MATTHEW J, PANDHI, NANCY · 2015 to 2024
$36.9M
University of New Mexico Clinical and Translational Science CenterUL1TR000041 · NCATS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI LARSON, RICHARD S · 2012 to 2014
$9.8M
NCATS NIH HHS UL1 TR000041NCATS NIH HHS UL1 TR001449
6 · The paper itself

Abstract

introduction and hypothesisMindfulness-based stress reduction (MBSR) is a standardized meditation program that may be an effective therapy for interstitial cystitis/bladder pain syndrome (IC/BPS), a condition exacerbated by stress. The aims of this study were to explore whether MBSR improved IC/BPS symptoms and the feasibility/acceptability of MSBR among women with IC/BPS.

methodsThis randomized controlled trial included women with IC/BPS undergoing first- or second-line therapies. Women were randomized to continuation of usual care (UC) or an 8-week MBSR class + usual care (MBSR). Participants completed baseline and 8-week post-treatment questionnaires, including the O'Leary-Sant Symptom Problem Index (OSPI), the visual analog pain scale (VAS), the Short Form Health Survey (SF-12), the Female Sexual Function Index (FSFI), and the Pain Self-Efficacy Questionnaire (PSEQ). The Global Response Assessment (GRA) was completed post-treatment. Analyses were performed using Student's t test, Chi-squared, and MANOVA where appropriate.

resultsEleven women were randomized to UC and 9 to MBSR, without differences in group characteristics. More MBSR participants' symptoms were improved on the GRA (7 out of 8 [87.5 %] vs 4 out of 11 [36.4 %], p = 0.03). The MBSR group showed greater improvement in the OSPI total (p = 0.0498) and problem scores (p = 0.036); the OSPI symptom score change did not differ. PSEQ scores improved in MBSR compared with UC (p = 0.035). VAS, SF-12, and FSFI change did not differ between groups. Eighty-six percent of MBSR participants felt more empowered to control symptoms, and all participants planned to continue MBSR.

conclusionsThis trial provides initial evidence that MBSR is a promising adjunctive therapy for IC/BPS. Its benefit may arise from patients' empowerment and ability to cope with symptoms.

Indexed as

AdultAnalysis of VarianceChi-Square DistributionCystitis, InterstitialFemaleHumansMiddle AgedMindfulnessQuality of LifeStress, PsychologicalSurveys and QuestionnairesTreatment OutcomeChronic painComplementary therapiesEmotional stressInterstitial cystitisMindfulness

Identifiers

PMID27116196
PMCPMC5067184

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.