Evidence map›Paper›PMID 27115524›Full record

ArticleZeitschrift fur Gerontologie und Geriatrie2017

Erythrocyte rheological properties but not whole blood and plasma viscosity are associated with severity of hypertension in older people.

Guo-Xiang Fu, Min Ji, Li-Zhi Han, Chan-Chan Xu, Feng-Feng Pan, Ting-Jun Hu, Yuan Zhong

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Zeitschrift fur Gerontologie und Geriatrie, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Guo-Xiang FuDepartment of Gerontology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, No. 600, Yi Shan Road, 200233, Shanghai, People's Republic of China.
Min JiDepartment of Gerontology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, No. 600, Yi Shan Road, 200233, Shanghai, People's Republic of China.
Li-Zhi HanDepartment of Gerontology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, No. 600, Yi Shan Road, 200233, Shanghai, People's Republic of China.
Chan-Chan XuDepartment of Gerontology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, No. 600, Yi Shan Road, 200233, Shanghai, People's Republic of China.
Feng-Feng PanDepartment of Gerontology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, No. 600, Yi Shan Road, 200233, Shanghai, People's Republic of China.
Ting-Jun HuDepartment of Gerontology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, No. 600, Yi Shan Road, 200233, Shanghai, People's Republic of China.
Yuan ZhongDepartment of Gerontology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, No. 600, Yi Shan Road, 200233, Shanghai, People's Republic of China. zhongyuan60@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study was carried out to determine whether changes in hemorheological parameters parallel the severity of essential hypertension.

methodsA total of 198 older hypertensive patients were recruited and classified into 3 stages of hypertension according to the grading standard of hypertension. The whole blood viscosity (WBV) at various shear rates, plasma viscosity and erythrocyte rheology (including erythrocyte rigidity index, erythrocyte aggregation index and erythrocyte deformation index) were examined.

resultsErythrocyte rheology paralleled the severity of essential hypertension and was significantly correlated to the average 24 h systolic blood pressure and diastolic blood pressure. Logistic analysis revealed that erythrocyte rigidity and the erythrocyte aggregation index were positively correlated with the severity of hypertension, while the erythrocyte deformation index was negatively correlated. No association was found between WBV, plasma viscosity and the severity of hypertension.

conclusionThe rheological properties of erythrocyte viscosity were correlated with the severity of hypertension in older people but the WBV and plasma viscosity were not.

Indexed as

Blood ViscosityErythrocytesSeverity of Illness IndexAged, 80 and overErythrocyte DeformabilityEssential HypertensionFemaleGeriatric AssessmentHematologic TestsHumansMalePlasmaReproducibility of ResultsSensitivity and SpecificityAgedBlood pressureBlood viscosityErythrocyte deformabilityVascular resistance

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.