ArticlePloS one2016
Long-Term Health-Related Quality of Life in German Patients with Juvenile Idiopathic Arthritis in Comparison to German General Population.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
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Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Health State Utility Values in Juvenile Idiopathic Arthritis: What is the Evidence?PharmacoEconomics · 2020Pooled it
- Lengthening sleep reduces pain in childhood arthritis: a crossover randomised controlled trial.RMD open · 2023Trial
- Comorbidities in Juvenile-Onset Rheumatic Diseases: A Systematic Review and Meta-Analysis.Children (Basel, Switzerland) · 2026Review
- Responsiveness of the EQ-5D-Y-5L Parent-Proxy Version Among Children with Juvenile Idiopathic Arthritis.The patient · 2026Article
- Symptoms and correlates of depression and anxiety in children and adolescents with juvenile idiopathic arthritis.Orphanet journal of rare diseases · 2026Article
- [Change of perspectives-goals in pediatric rheumatology].Zeitschrift fur Rheumatologie · 2026Review
- What have we learned from long-term studies in juvenile idiopathic arthritis? - Prediction, classification, transition.Pediatric rheumatology online journal · 2025Review
- Disease activity and treatment in patients with juvenile idiopathic arthritis before transfer to adult care: the first survey in China.Frontiers in pediatrics · 2025Article
- Pediatric to adult rheumatology transition: Success rates, influencing factors, and evolving diagnoses and treatments.Archives of rheumatology · 2024Article
- Real-world psychosocial impact among patients with juvenile idiopathic arthritis and families in Spain.Pediatric rheumatology online journal · 2024Observational
- Quality of life and healthcare costs of patients with allergic respiratory diseases: a cross-sectional study.The European journal of health economics : HEPAC : health economics in prevention and care · 2024Article
- Predicting comorbid mental health difficulties in people with autoimmune arthritis.Rheumatology international · 2024Article
- Influence of the timing of biological treatment initiation on Juvenile Idiopathic Arthritis long-term outcomes.Arthritis research & therapy · 2023Article
- Prevalence and risk factors of depressive symptoms in children and adolescents with juvenile idiopathic arthritis.Rheumatology international · 2023Article
- Risk of Psychiatric Disorders in Juvenile Idiopathic Arthritis: Population- and Sibling-Controlled Cohort and Cross-Sectional Analyses.ACR open rheumatology · 2023Article
- Is time a healer? How quality of life changes over time reported by parents of children and young people with juvenile idiopathic arthritis.Rheumatology (Oxford, England) · 2023Article
- Physical Activity Influences Health-Related Quality of Life in Adults with Juvenile Idiopathic Arthritis.Journal of clinical medicine · 2023Article
- Health-related quality of life, continuity of care and patient satisfaction: long-term outcomes of former patients of the Tuebingen Transition Program (TTP) - a retrospective cohort study.Pediatric rheumatology online journal · 2022Article
- Costs of Hospital-Associated Care for Patients With Juvenile Idiopathic Arthritis in the Dutch Health Care System.Arthritis care & research · 2022Article
- Examining Health Outcomes in Juvenile Idiopathic Arthritis: A Genetic Epidemiology Study.ACR open rheumatology · 2022Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveAims of the study were to investigate health-related quality of life (HRQOL) in adult patients with former diagnosis of Juvenile Idiopathic Arthritis (JIA), to compare their HRQOL with the general population and to identify factors related to a poor outcome.
methodsIn 2012, a cross-sectional survey was performed by mailing a questionnaire to a large cohort of former and current patients of the German Centre for Rheumatology in Children and Adolescents. Only adult patients (≥18 years) with a diagnosis compatible with JIA were included (n = 2592; response 66%). The questionnaire included information about HRQOL (EQ5D), disease-related questions and socio-demographics. Prevalence and 95% confidence intervals (CI) of problems with mobility, self-care, usual activities, pain and anxiety/depression were standardized to the German general population. Factors associated with low HRQOL in JIA patients were identified using logistic regression models.
resultsSixty-two percent of the study population was female; age range was 18-73 years. In all dimensions, JIA patients reported statistically significantly more problems than the general population with largest differences in the pain dimension (JIA patients 56%; 95%CI 55-58%; general population 28%; 26-29%) and the anxiety/depression dimension (28%; 27-29% vs. 4%; 4-5%). Lower HRQOL in JIA patients was associated with female sex, older age, lower level of education, still being under rheumatic treatment and disability.
conclusionsHRQOL in adult JIA patients is considerably lower than in the general population. As this cohort includes historic patients the new therapeutic schemes available today are expected to improve HRQOL in future.
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