ArticleClinical interventions in aging2016
Height and sex is strongly associated with radial augmentation index in Korean patients with never-treated hypertension.
Article in Clinical interventions in aging, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- The moderating effect of fluid overload on the relationship between the augmentation index and left ventricular diastolic function in patients with CKD.Scientific reports · 2024Article
- Comparison of Risk of Target Organ Damage in Different Phenotypes of Arterial Stiffness and Central Aortic Blood Pressure.Frontiers in cardiovascular medicine · 2022Article
- Endovascular Revascularization Improves the Central Hemodynamics and Augmentation Index in Patients with Peripheral Artery Disease.Internal medicine (Tokyo, Japan) · 2020Article
- Stressful life events and augmentation index: results from the Cardiovascular and Metabolic Diseases Etiology Research Center.Hypertension research : official journal of the Japanese Society of Hypertension · 2020Article
- Cuff-Based Oscillometric Measurements of Central Hemodynamics: Factors Influencing Central Augmentation Pressure in Normotensive Japanese Individuals.Pulse (Basel, Switzerland) · 2019Article
- The serum sclerostin level is positively associated with the aortic augmentation index in patients on peritoneal dialysis.Tzu chi medical journalArticle
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Authors and funding
13 authors.
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Abstract
objectivesCentral hemodynamics may better represent the load imposed on the coronary and cerebral arteries and thereby bear a stronger relationship to cardiovascular outcomes.
methodsPatients who had confirmed hypertension as assessed by daytime 24-hour ambulatory blood pressure monitoring (≥135/85 mmHg) were enrolled. Central blood pressure and radial augmentation index (AIx) corrected for a heart rate of 75 bpm (radial AIx 75) were measured for all patients. We evaluated the association of age, height, and sex with central hemodynamics in patients with never-treated hypertension.
resultsA total of 203 patients were enrolled, of whom men numbered 101 (49.7%). The median height of all patients was 162 cm, and mean age was 53.2 years. In the Pearson correlation analysis, regardless of sex difference (R=-0.627 for height, R=0.035 for age, P-value =0.005), a stronger relationship was observed between height and radial AIx 75 than between age and radial AIx 75. In the multiple regression analysis, the sex difference and height were strongly associated with elevated radial AIx 75 in all patients (adjusted R (2)=0.428, β=6.237, 95% confidence interval [CI] for women 1.480-10.995, P-value =0.011 and β=-0.632, 95% CI for height -0.929 to -0.335, P-value =0.009, respectively).
conclusionIn patients with never-treated hypertension, female sex and shorter height are the important risk factors of elevated radial AIx 75.
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