Evidence map›Paper›PMID 27114611›Full record

ArticleThe Journal of general physiology2016

Approaching ryanodine receptor therapeutics from the calcin angle.

Josefina Ramos-Franco, Michael Fill

Abstract read
In one paragraph

Article in The Journal of general physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Single-Residue Substitution of Opicalcin1 Enhances Cellular Uptake but Reduces CaChembiochem : a European journal of chemical biology · 2026
    Article
  2. Australian ScorpionBiomolecules · 2020
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Josefina Ramos-FrancoDepartment of Molecular Biophysics and Physiology, Rush University Medical Center, Chicago, IL 60612.
Michael FillDepartment of Molecular Biophysics and Physiology, Rush University Medical Center, Chicago, IL 60612 Michael_Fill@rush.edu.

Funding

Limiting Pathological Calcium Induced Calcium Release in HeartR01HL057832 · NHLBI · RUSH UNIVERSITY MEDICAL CENTER · PI FILL, MICHAEL, GILLESPIE, DIRK · 1997 to 2024
$9.0M
Skeletal Muscle Ryanodine Receptor Permeation and Self Counter-Ion FlowR01AR054098 · NIAMS · RUSH UNIVERSITY MEDICAL CENTER · PI FILL, MICHAEL · 2007 to 2017
$2.9M
Control of IP3R-Mediated Calcium ReleaseR01GM111397 · NIGMS · RUSH UNIVERSITY MEDICAL CENTER · PI CHEN, SUI RONG WAYNE, FILL, MICHAEL · 2015 to 2018
$1.6M
NHLBI NIH HHS R01 HL057832NIAMS NIH HHS R01 AR054098NIGMS NIH HHS R01 GM111397
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCalciumCalcium SignalingGene Expression RegulationHumansPeptidesRyanodine Receptor Calcium Release ChannelScorpion VenomsCalciumPeptidesRyanodine Receptor Calcium Release ChannelScorpion Venoms

Identifiers

PMID27114611
PMCPMC4845691

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.