ArticleProceedings of the National Academy of Sciences of the United States of America2016
Reticulate evolution is favored in influenza niche switching.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Characterization of bovine-derived H5N1 viruses expressing fluorescent and luminescent reporter proteins.The Journal of general virology · 2026Article
- Assessing the impact of phylogenetic reconstruction error on genetic reassortment inference in segmented viruses.PloS one · 2026Article
- Global dynamics of avian influenza: a twenty-year analysis of highly pathogenic viruses linking the Caspian Basin, Eurasia and Africa sectors (2005-2025).Frontiers in cellular and infection microbiology · 2026Review
- Pandemic risk stemming from the bovine H5N1 outbreak: an account of the knowns and unknowns.Journal of virology · 2025Review
- The evolution and epidemiology of H3N2 canine influenza virus after 20 years in dogs.Epidemiology and infection · 2025Article
- Article
- The global H5N1 influenza panzootic in mammals.Nature · 2025Review
- Article
- Multiple transatlantic incursions of highly pathogenic avian influenza clade 2.3.4.4b A(H5N5) virus into North America and spillover to mammals.Cell reports · 2024Article
- Panzootic HPAIV H5 and risks to novel mammalian hosts.Npj viruses · 2024Article
- Influenza A virus coinfection dynamics are shaped by distinct virus-virus interactions within and between cells.PLoS pathogens · 2023Article
- Global dissemination of influenza A virus is driven by wild bird migration through arctic and subarctic zones.Molecular ecology · 2023Article
- Influenza A virus reassortment in mammals gives rise to genetically distinct within-host subpopulations.Nature communications · 2022Article
- Modeling cellular co-infection and reassortment of bluetongue virus inVirus evolution · 2022Article
- Complementary Effects of Virus Population Are Required for Efficient Virus Infection.Frontiers in microbiology · 2022Article
- Identifying vulnerable populations and transmission pathways by geographic correlation of the environment to human health.The Science of the total environment · 2021Article
- Article
- H5N8 and H7N9 packaging signals constrain HA reassortment with a seasonal H3N2 influenza A virus.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Article
- It's in the mix: Reassortment of segmented viral genomes.PLoS pathogens · 2018Review
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Authors and funding
5 authors.
Funding
Abstract
Reticulate evolution is thought to accelerate the process of evolution beyond simple genetic drift and selection, helping to rapidly generate novel hybrids with combinations of adaptive traits. However, the long-standing dogma that reticulate evolutionary processes are likewise advantageous for switching ecological niches, as in microbial pathogen host switch events, has not been explicitly tested. We use data from the influenza genome sequencing project and a phylogenetic heuristic approach to show that reassortment, a reticulate evolutionary mechanism, predominates over mutational drift in transmission between different host species. Moreover, as host evolutionary distance increases, reassortment is increasingly favored. We conclude that the greater the quantitative difference between ecological niches, the greater the importance of reticulate evolutionary processes in overcoming niche barriers.
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