Evidence map›Paper›PMID 27114331›Full record

ArticleFertility and sterility2016

Novel correlates between antimüllerian hormone and menstrual cycle characteristics in African-American women (23-35 years-old).

Erica E Marsh, Lia A Bernardi, Marissa L Steinberg, Peter J de Chavez, Jenny A Visser, Mercedes R Carnethon, Donna D Baird

Open access · bronzeAbstract read
In one paragraph

Article in Fertility and sterility, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

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  7. MOTHER Study: AJournal of obstetrics and gynaecology of India · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Erica E MarshDepartment of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, Northwestern University Feinberg School of Medicine, Chicago, Illinois. Electronic address: erica-marsh@northwestern.edu.
Lia A BernardiDepartment of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Marissa L SteinbergDepartment of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Peter J de ChavezDepartment of Preventive Medicine, Northwestern University, Chicago, Illinois.
Jenny A VisserDepartment of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.
Mercedes R CarnethonDepartment of Preventive Medicine, Northwestern University, Chicago, Illinois.
Donna D BairdEpidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina.
Northwestern University · USErasmus MC · NLNational Institutes of Health · US

Funding

Uterine Leiomyoma Research Center ProgramP01HD057877 · NICHD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI BULUN, SERDAR E. · 2009 to 2019
$12.2M
Research Career Development in Obstetrics and GynecologyK12HD050121 · NICHD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Serdar E. Bulun · 2005 to 2026
$7.2M
Environmental Effects On FertilityZIAES049003 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI BAIRD, DONNA D. · 2009 to 2023
$3.3M
ENVIRONMENTAL EFFECTS ON FERTILITYZ01ES049003 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI BAIRD, DONNA D. · 1990 to 2008
$1.1M
Role of MicroRNA-29 in Uterine Leiomyoma PathogenesisR21HD077479 · NICHD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MARSH, ERICA E · 2013 to 2014
$419k
Intramural NIH HHS Z01 ES049003NICHD NIH HHS K12 HD050121NICHD NIH HHS P01 HD057877NICHD NIH HHS R21 HD077479
6 · The paper itself

Abstract

objectiveTo characterize normative antimüllerian hormone (AMH) levels and ascertain which factors are associated with AMH in a large cohort of reproductive-age women.

designCross-sectional study.

settingNot applicable. PATIENT(S): A total of 1,654 African-American women (AAW) ages 23-34 at recruitment. INTERVENTION(S): Not applicable. MAIN OUTCOME MEASURE(S): Serum AMH measured using an ultrasensitive ELISA. RESULT(S): The median AMH was 3.18 ng/mL, and there was a significant, but nonlinear, relationship between age and AMH, with levels peaking at age 25. As AMH was not normally distributed, log transformation was performed and used for all analyses. In a multivariable age-adjusted model, body mass index, current use of hormonal contraception, and history of a thyroid condition were inversely associated with AMH, while history of abnormal menstrual bleeding and menstrual cycles longer than 35 days were positively associated with AMH. CONCLUSION(S): While age is correlated with AMH, it accounts for only a portion of the variation seen. This study adds valuable information to the existing literature on normative AMH levels in young reproductive-age women. While our findings fill a critical data gap for ovarian reserve in AAW, the insights gained will be of benefit for all women.

Indexed as

Black or African AmericanOvarian ReserveAdultAge FactorsAnti-Mullerian HormoneBiomarkersCross-Sectional StudiesEnzyme-Linked Immunosorbent AssayFemaleHumansLinear ModelsMenstrual CycleMichiganMultivariate AnalysisYoung AdultAnti-Mullerian HormoneBiomarkersAfrican-American womenAMHovarian reserve

Identifiers

PMID27114331
PMCPMC4975664
OpenAlexW2337563933

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.