Evidence map›Paper›PMID 27114114›Full record

ReviewJournal of neuroendocrinology2016

Neuroendocrine Regulation of Metabolism.

M P Cornejo, S T Hentges, M Maliqueo, H Coirini, D Becu-Villalobos, C F Elias

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of neuroendocrinology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 54 citations in OpenAlex.

  1. Trial
  2. Trial
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  4. Tanycyte-derived lactate activates astrocytic HCAR1 to modulate glutamatergic signaling and POMC neuron excitability.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
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  7. Review
  8. Review
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  11. Article
  12. Review
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  14. Review
  15. Article
  16. Neuro-toxic and Reproductive Effects of BPA.Current neuropharmacology · 2019
    Review
  17. Article
  18. Article
  19. Article
  20. Impact of Dietary Fats on Brain Functions.Current neuropharmacology · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 3 countries.

M P CornejoLaboratory of Neurophysiology, Multidisciplinary Institute of Cell Biology [IMBICE, dependent on the Argentine Research Council (CONICET), Scientific Research Commission, Province of Buenos Aires (CIC-PBA) and National University of La Plata (UNLP)], La Plata, Argentina.
S T HentgesDepartment of Biomedical Sciences, Colorado State University, Fort Collins, CO, USA.
M MaliqueoEndocrinology and Metabolism Laboratory, Department of Medicine West Division, School of Medicine University of Chile, Santiago de Chile, Chile.
H CoiriniLaboratory of Neurobiology, Institute of Biology and Experimental Medicine [(IBYME), dependent on CONICET] and Department of Human Biochemistry, University of Buenos Aires, Buenos Aires, Argentina.
D Becu-VillalobosLaboratory of Pituitary Regulation, Institute of Biology and Experimental Medicine [(IBYME), dependent on CONICET], Buenos Aires, Argentina.
C F EliasMolecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA.
Experimental Medicine and Biology Institute · ARColorado State University · USUniversidad Nacional de La Plata · ARUniversity of Chile · CLUniversity of Michigan–Ann Arbor · US

Funding

Pilot and Feasibility (P and F) ProgramP30DK089503 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Joyce Lee · 2010 to 2026
$20.3M
Hypothalmic Circuits Regulating Energy Balance and Obesity: Synaptic PhysiologyR01DK078749 · NIDDK · WASHINGTON STATE UNIVERSITY · PI HENTGES, SHANE T · 2008 to 2021
$4.6M
Neural basis of leptin action on reproductionR01HD069702 · NICHD · UT SOUTHWESTERN MEDICAL CENTER · PI ELIAS, CAROL FUZETI · 2012 to 2021
$3.4M
NICHD NIH HHS R01 HD069702NIDDK NIH HHS P30 DK089503NIDDK NIH HHS R01 DK078749
6 · The paper itself

Abstract

Given the current environment in most developed countries, it is a challenge to maintain a good balance between calories consumed and calories burned, although maintenance of metabolic balance is key to good health. Therefore, understanding how metabolic regulation is achieved and how the dysregulation of metabolism affects health is an area of intense research. Most studies focus on the hypothalamus, which is a brain area that acts as a key regulator of metabolism. Among the nuclei that comprise the hypothalamus, the arcuate nucleus is one of the major mediators in the regulation of food intake. The regulation of energy balance is also a key factor ensuring the maintenance of any species as a result of the dependence of reproduction on energy stores. Adequate levels of energy reserves are necessary for the proper functioning of the hypothalamic-pituitary-gonadal axis. This review discusses valuable data presented in the 2015 edition of the International Workshop of Neuroendocrinology concerning the fundamental nature of the hormonal regulation of the hypothalamus and the impact on energy balance and reproduction.

Indexed as

AnimalsEnergy MetabolismHumansHypothalamusReproductionenergy balancehypothalamusreproduction

Identifiers

PMID27114114
PMCPMC4956544
OpenAlexW2344613421

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.