Evidence map›Paper›PMID 27113813›Full record

ArticleInternational journal of geriatric psychiatry2017

Psychotropic drugs and the risk of fall injuries, hospitalisations and mortality among older adults.

Kristina Johnell, Gudrun Jonasdottir Bergman, Johan Fastbom, Bengt Danielsson, Natalia Borg, Peter Salmi

Abstract read
In one paragraph

Article in International journal of geriatric psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed, 2 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kristina JohnellAging Research Center, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden.
Gudrun Jonasdottir BergmanThe Swedish National Board of Health and Welfare (Socialstyrelsen), Stockholm, Sweden.
Johan FastbomAging Research Center, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden.
Bengt DanielssonThe Swedish National Board of Health and Welfare (Socialstyrelsen), Stockholm, Sweden.
Natalia BorgThe Swedish National Board of Health and Welfare (Socialstyrelsen), Stockholm, Sweden.
Peter SalmiThe Swedish National Board of Health and Welfare (Socialstyrelsen), Stockholm, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate whether psychotropics are associated with an increased risk of fall injuries, hospitalizations, and mortality in a large general population of older adults.

methodsWe performed a nationwide matched (age, sex, and case event day) case-control study between 1 January and 31 December 2011 based on several Swedish registers (n = 1,288,875 persons aged ≥65 years). We used multivariate conditional logistic regression adjusted for education, number of inpatient days, Charlson co-morbidity index, dementia and number of other drugs.

resultsAntidepressants were the psychotropic most strongly related to fall injuries (OR

conclusionsOur findings support a cautious prescribing of multiple psychotropic drugs to older patients. © 2016 The Authors. International Journal of Geriatric Psychiatry Published by John Wiley & Sons, Ltd.

Indexed as

MortalityAccidental FallsAgedAged, 80 and overAntidepressive AgentsAntipsychotic AgentsCase-Control StudiesComorbidityFemaleHospitalizationHumansLogistic ModelsMaleMental DisordersPsychotropic DrugsSwedenAntidepressive AgentsAntipsychotic AgentsPsychotropic Drugsageddementiapsychotropic drugsSweden

Identifiers

PMID27113813
PMCPMC5347947

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.