ArticleNature communications2016
Protein-directed self-assembly of a fullerene crystal.
Article in Nature communications, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed.
- Next Generation Hosts for Protein Recognition, Assembly and More.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026Review
- Duplex-forming oligocarbamates with tunable nonbonding sites.Chemical science · 2024Article
- Recent advances in supramolecular fullerene chemistry.Chemical Society reviews · 2024Review
- Enhanced Uptake and Phototoxicity of CNanomaterials (Basel, Switzerland) · 2022Article
- Supramolecular assembly of protein building blocks: from folding to function.Nano convergence · 2022Review
- Dissecting the Supramolecular Dispersion of Fullerenes by Proteins/Peptides: Amino Acid Ranking and Driving Forces for Binding to CInternational journal of molecular sciences · 2021Article
- Characteristics and therapeutic applications of antimicrobial peptides.Biophysics reviews · 2021Review
- CActa crystallographica Section B, Structural science, crystal engineering and materials · 2020Article
- The Human LL-37(17-29) antimicrobial peptide reveals a functional supramolecular structure.Nature communications · 2020Article
- Atomic Details of Carbon-Based Nanomolecules Interacting with Proteins.Molecules (Basel, Switzerland) · 2020Review
- Review
- Rationally Designed Protein Building Blocks for Programmable Hierarchical Architectures.Frontiers in chemistry · 2020Review
- General lack of structural characterization of chemically synthesized long peptides.Protein science : a publication of the Protein Society · 2019Review
- Construction of supramolecular nanotubes from protein crystals.Chemical science · 2019Article
- Exploring the Inhibitory and Antioxidant Effects of Fullerene and Fullerenol on Ribonuclease A.ACS omega · 2018Article
- Spectroscopic and metal binding properties of a de novo metalloprotein binding a tetrazinc cluster.Biopolymers · 2018Article
- Antimicrobial activity of a porphyrin binding peptide.Peptide science (Hoboken, N.J.) · 2018Article
- Hierarchical design of artificial proteins and complexes toward synthetic structural biology.Biophysical reviews · 2018Review
- Design of self-assembling transmembrane helical bundles to elucidate principles required for membrane protein folding and ion transport.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017Review
- Structure of the Anti-C60 Fullerene Antibody Fab Fragment: Structural Determinants of Fullerene Binding.Acta naturaeArticle
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
Learning to engineer self-assembly would enable the precise organization of molecules by design to create matter with tailored properties. Here we demonstrate that proteins can direct the self-assembly of buckminsterfullerene (C60) into ordered superstructures. A previously engineered tetrameric helical bundle binds C60 in solution, rendering it water soluble. Two tetramers associate with one C60, promoting further organization revealed in a 1.67-Å crystal structure. Fullerene groups occupy periodic lattice sites, sandwiched between two Tyr residues from adjacent tetramers. Strikingly, the assembly exhibits high charge conductance, whereas both the protein-alone crystal and amorphous C60 are electrically insulating. The affinity of C60 for its crystal-binding site is estimated to be in the nanomolar range, with lattices of known protein crystals geometrically compatible with incorporating the motif. Taken together, these findings suggest a new means of organizing fullerene molecules into a rich variety of lattices to generate new properties by design.
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Registered trials
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