Evidence map›Paper›PMID 27113338›Full record

ArticleHead & face medicine2016

Oral lichen planus clinical characteristics in Italian patients: a retrospective analysis.

Dorina Lauritano, Mariantonietta Arrica, Alberta Lucchese, Marina Valente, Giuseppe Pannone, Carlo Lajolo, Rossella Ninivaggi, Massimo Petruzzi

Open access · goldAbstract read
In one paragraph

Article in Head & face medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 77 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Dorina LauritanoDepartment of Translational Medicine and Surgery Neuroscience Centre of Milan, University of Milano Bicocca, Monza, Italy.
Mariantonietta ArricaDental School of University of Sassari, Sassari, Italy.
Alberta LuccheseDental Clinic of Second Universty of Naples (SUN), Naples, Italy.
Marina ValenteSection of Pathology of University of Foggia, Foggia, Italy.
Giuseppe PannoneSection of Pathology of University of Foggia, Foggia, Italy.
Carlo LajoloSchool of Dentistry, Chatolic University, Rome, Italy.
Rossella NinivaggiInterdisciplinary Department of Medicine (DIM) - Section of Dentistry, University "Aldo Moro" of Bari, Clinica odontoiatrica del Policlinico di Bari, Piazza Giulio Cesare 11, 70124, Bari, Italy.
Massimo PetruzziInterdisciplinary Department of Medicine (DIM) - Section of Dentistry, University "Aldo Moro" of Bari, Clinica odontoiatrica del Policlinico di Bari, Piazza Giulio Cesare 11, 70124, Bari, Italy. massimo.petruzzi@uniba.it.
Ospedale Pediatrico Giovanni XXIII · ITUniversity of Foggia · ITUniversity of Milano-Bicocca · ITUniversity of Sassari · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOral lichen Planus (OLP) is a chronic inflammatory disease involving skin and mucous membranes. Its etiology is still uncertain whilst an autoimmune mechanism is known to be implicated. OLP is commonly considered a geriatric disease and gender differences in prevalence are clear, whereby females are generally more frequently affected than males more often during the 5th and 6th decades of life. Lesions are symmetrical and bilateral and the buccal mucosa is frequently involved. The risk of malignant transformation is extremely low. This study aims to describe both the clinical characteristics and the prevalence of OLP among a group of patients from Southern Italy. The results of the present study were compared to analogous retrospective studies.

methodsEighty-seven (31 man and 56 woman) cases of OLP were retrospectively reviewed and demographic and clinical data were collected. Data about OLP as clinical forms, oral and extraoral sites involved and Visual Analogue Scale were also recorded.

resultsThe average age of OLP onset was 59.2 years. The most common clinical presentation was the hyperkeratosic type. Symptomatic OLP was noted in 26.8 % of the patiens. The most frequently affected oral sites were buccal mucosa, tongue, gums. The most frequently associated systemic diseases were diabetes, hypertension, C hepatitis and thyroiditis. Only one patient developed a malignant transformation (1.2 %).

conclusionsPrevious retrospective studies report data partially comparable with our results. Different geographic area, number of enrolled patients and OLP classification criteria may justify the observed differences.

Indexed as

Adrenal Cortex HormonesAgedAged, 80 and overCalcineurin InhibitorsClobetasolDrug Therapy, CombinationFemaleHumansItalyLichen Planus, OralMaleMiddle AgedPain MeasurementRetrospective StudiesTreatment OutcomeAdrenal Cortex HormonesCalcineurin InhibitorsClobetasolAutoimmune diseasesOral lichen planusRetrospective study

Identifiers

PMID27113338
PMCPMC4845340
OpenAlexW2344291409

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.