ReviewJournal of proteomics2016
Targeted proteomics: Current status and future perspectives for quantification of food allergens.
Review in Journal of proteomics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Proteomic Characterization of Major Fish Allergy Responsive Protein Parvalbumins in Hilsa (Journal of agricultural and food chemistry · 2025Article
- Allergens in Food: Analytical LC-MS/MS Method for the Qualitative Detection ofFoods (Basel, Switzerland) · 2025Article
- Proteomics in Inherited Metabolic Disorders.International journal of molecular sciences · 2022Review
- Lentil allergens identification and quantification: An update from omics perspective.Food chemistry. Molecular sciences · 2022Review
- Targeted proteomics and specific immunoassays reveal the presence of shared allergens between the zoonotic nematodes Anisakis simplex and Pseudoterranova decipiens.Scientific reports · 2022Article
- Targeted proteomics for the analysis of cultural heritage: application of broadband collision-induced dissociation mass spectrometry.Analytical and bioanalytical chemistry · 2022Article
- Proteomic Advances in Cereal and Vegetable Crops.Molecules (Basel, Switzerland) · 2021Review
- Application of Mass Spectrometry-Based Proteomics to Barley Research.Journal of agricultural and food chemistry · 2021Review
- The History, Present and Future of Allergen Standardization in the United States and Europe.Frontiers in immunology · 2021Review
- Multi-Omics Approach in the Identification of Potential Therapeutic Biomolecule for COVID-19.Frontiers in pharmacology · 2021Review
- Review
- Use of IHF-QD Microscopic Analysis for the Detection of Food Allergenic Components: Peanuts and Wheat Protein.Foods (Basel, Switzerland) · 2020Article
- Mycoprotein: environmental impact and health aspects.World journal of microbiology & biotechnology · 2019Review
- Large Scale Proteomic Data and Network-Based Systems Biology Approaches to Explore the Plant World.Proteomes · 2018Article
- Tailored Use of Targeted Proteomics in Plant-Specific Applications.Frontiers in plant science · 2018Article
- Mass spectrometry-assisted gel-based proteomics in cancer biomarker discovery: approaches and application.Theranostics · 2017Review
- Using Proteomics to Understand How Leishmania Parasites Survive inside the Host and Establish Infection.International journal of molecular sciences · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
unlabelledAllergen levels in fresh and processed foods can vary dynamically. As different sources of foods can cause different types of allergic reactions, the food industry and regulatory bodies urgently require reliable detection and absolute quantitation methods for allergen detection in complex food products to effectively safeguard the food-allergic population. Recent advances of targeted proteomic technologies namely multiple-reaction monitoring (MRM) mass spectrometry (MS) coupled with isotope-labeled internal standard, also known as AQUA peptides offers absolute quantitation of food allergens even at 10ppb level in a multiplex fashion. However, development of successful AQUA-MRM assay relies on a number of pre and post MS criteria. In this review, we briefly describe how allergen levels could potentially change in plant and animal based foods, necessitating the development of a high throughput multiplexed allergen quantification methodology for successful AQUA-MRM assay. We also propose some future strategies that could provide better management of food allergy. BIOLOGICAL SIGNIFICANCE: Given the rapid increases of food allergenicity, it has become imperative to know absolute allergen levels in foods. This essential information could be the most effective means of protecting humans suffering from allergies. In this review, we emphasize the significance of the absolute quantitation of food allergens using AQUA-MRM approach and discuss the likely critical steps for successful assay development.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.