ArticleHypertension (Dallas, Tex. : 1979)2016
Preconception Cardiovascular Risk Factor Differences Between Gestational Hypertension and Preeclampsia: Cohort Norway Study.
Article in Hypertension (Dallas, Tex. : 1979), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 2 of them syntheses that pooled it.
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Who cites it
53 citing papers in PubMed, 2 syntheses or guidelines pooled it, 92 citations in OpenAlex.
- Parental genetically predicted liability for coronary heart disease and risk of adverse pregnancy outcomes: a cohort study.BMC medicine · 2024Pooled it
- The association of malaria infection and gestational hypertension in Africa: Systematic review and meta-analysis.Journal of global health · 2020Pooled it
- Circulating Cardiovascular Biomarkers 1-3 Years Following Hypertensive Pregnancy Disorders: Associations With Postpartum Cardiovascular Structure and Function.Reproductive sciences (Thousand Oaks, Calif.) · 2026Article
- Association Between Total Cholesterol-to-High-Density Lipoprotein Ratio and Gestational Hypertension: A Case-Control Study.Medical science monitor : international medical journal of experimental and clinical research · 2026Article
- Cardiac Implications of Preeclampsia: A Review.Journal of personalized medicine · 2026Review
- Interplay Among Endothelial Dysfunction, NLRP3 Pathway Activation, and microRNAs in the Pathogenesis of Preeclampsia.Diseases (Basel, Switzerland) · 2026Review
- Exploring Maternal Mental Health Conditions and Urban-Rural Disparities in Hypertensive Disorders of Pregnancy in South Carolina: A Fairlie Decomposition Approach.Maternal and child health journal · 2026Article
- The Effect of a Supervised Exercise Program Throughout Pregnancy on Longitudinal Lipid Profile Changes: A Randomized Clinical Trial.Maternal-fetal medicine (Wolters Kluwer Health, Inc.) · 2026Article
- The effect of maternal pre-pregnancy body mass index on hypertensive disorders of pregnancy (HDP): a systematic review and dose-response meta-analysis of cohort studies involving 50 million pregnancies.EClinicalMedicine · 2025Article
- Preconception Physical Activity and Maternal Health Outcomes: An Integrative Review of Studies from 2016-2025.Maternal and child health journal · 2025Review
- Pre conception dyslipidemia and risk for preeclampsia in women undergoing IVF ET.Scientific reports · 2025Article
- Impact of Sex Differences on Lipids and Statin Utilization.Current atherosclerosis reports · 2025Review
- First trimester circulating miR-208b-3p and miR-26a-1-3p are relevant to the prediction of gestational hypertension.BMC pregnancy and childbirth · 2025Article
- Clinical Analysis of Risk Factors and Perinatal Outcomes in Recurrent Pre-Eclampsia with Severe Features.Reproductive sciences (Thousand Oaks, Calif.) · 2024Article
- Unique features of dyslipidemia in women across a lifetime and a tailored approach to management.American journal of preventive cardiology · 2024Review
- Pathophysiology of Pre-Eclampsia-Two Theories of the Development of the Disease.International journal of molecular sciences · 2023Review
- Understanding the Role of Chemerin in the Pathophysiology of Pre-Eclampsia.Antioxidants (Basel, Switzerland) · 2023Review
- Association between preeclampsia in daughters and risk of cardiovascular disease in parents.European journal of epidemiology · 2023Article
- Prevalence of traditional and non-traditional cardiovascular risk factors in adults with congenital heart disease.International journal of cardiology. Congenital heart disease · 2023Article
- Modifiable Risk Factors for Cardiovascular Disease among Women with and without a History of Hypertensive Disorders of Pregnancy.Nutrients · 2023Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Preconception predictors of gestational hypertension and preeclampsia may identify opportunities for early detection and improve our understanding of the pathogenesis and life course epidemiology of these conditions. Female participants in community-based Cohort Norway health surveys, 1994 to 2003, were prospectively followed through 2012 via record linkages to Medical Birth Registry of Norway. Analyses included 13 217 singleton pregnancies (average of 1.59 births to 8321 women) without preexisting hypertension. Outcomes were gestational hypertension without proteinuria (n=237) and preeclampsia (n=429). Mean age (SD) at baseline was 27.9 years (4.5), and median follow-up was 4.8 years (interquartile range 2.6-7.8). Gestational hypertension and preeclampsia shared several baseline risk factors: family history of diabetes mellitus, pregravid diabetes mellitus, a high total cholesterol/high-density lipoprotein cholesterol ratio (>5), overweight and obesity, and elevated blood pressure status. For preeclampsia, a family history of myocardial infarction before 60 years of age and elevated triglyceride levels (≥1.7 mmol/L) also predicted risk while physical activity was protective. Preterm preeclampsia was predicted by past-year binge drinking (≥5 drinks on one occasion) with an adjusted odds ratio of 3.7 (95% confidence interval 1.3-10.8) and by past-year physical activity of ≥3 hours per week with an adjusted odds ratio of 0.5 (95% confidence interval 0.3-0.8). The results suggest similarities and important differences between gestational hypertension, preeclampsia, and preterm preeclampsia. Modifiable risk factors could be targeted for improving pregnancy outcomes and the short- and long-term sequelae for mothers and offspring.
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