ReviewPediatric rheumatology online journal2016
Therapeutic advances in the treatment of vasculitis.
Review in Pediatric rheumatology online journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Associations between interleukin 18 gene polymorphisms and susceptibility to vasculitis: A meta-analysis.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2020Pooled it
- Pulmonary Artery Aneurysm (PAA) in Behçet's Disease Presenting With Recurrent Hemoptysis: A Case Report.Clinical case reports · 2025Article
- Study on the correlation between atmospheric pollutants and the development of IgA vasculitis.Medicine · 2025Observational
- The Impact of High Dose Glucocorticoids on Bone Health and Fracture Risk in Systemic Vasculitides.Frontiers in endocrinology · 2022Review
- Assessment of the association between red blood cell distribution width and disease activity in patients with systemic vasculitis.Experimental and therapeutic medicine · 2021Article
- Leukocytoclastic vasculitis associated with multifocal sensory neuropathy responsive to intravenous immunoglobulins: a case report.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2021Article
- Biologics for childhood systemic vasculitis.Pediatric nephrology (Berlin, Germany) · 2019Review
- Continuous infusion of lipo-prostaglandin E1 for Takayasu's arteritis with heart failure in an 11-month-old baby: a case report.Journal of medical case reports · 2018Article
- Vasculitis update: pathogenesis and biomarkers.Pediatric nephrology (Berlin, Germany) · 2018Review
- Kawasaki Disease.Frontiers in pediatrics · 2018Review
- Efficacy of mizoribine and prednisolone combination therapy in adult patients with IgA vasculitis.Rheumatology international · 2017Article
- ATS Core Curriculum 2017: Part II. Pediatric Pulmonary Medicine.Annals of the American Thoracic Society · 2017Review
- [Hypertension and intermittent convulsions for one month in a school-age child].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2017Article
- Optic Neuropathy Secondary to Polyarteritis Nodosa, Case Report, and Diagnostic Challenges.Frontiers in neurology · 2017Article
- Intravenous immunoglobulins in Henoch-Schönlein purpura with severe gastrointestinal involvement. Case report and review of the literature.International journal of immunopathology and pharmacologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Considerable therapeutic advances for the treatment of vasculitis of the young have been made in the past 10 years, including the development of outcome measures that facilitate clinical trial design. Notably, these include: a recognition that some patients with Kawasaki Disease require corticosteroids as primary treatment combined with IVIG; implementation of rare disease trial design for polyarteritis nodosa to deliver the first randomised controlled trial for children; first clinical trials involving children for anti-neutrophil cytoplasmic antibody (ANCA) vasculitis; and identification of monogenic forms of vasculitis that provide an understanding of pathogenesis, thus facilitating more targeted treatment. Robust randomised controlled trials for Henoch Schönlein Purpura nephritis and Takayasu arteritis are needed; there is also an over-arching need for trials examining new agents that facilitate corticosteroid sparing, of particular importance in the paediatric population since glucocorticoid toxicity is a major concern.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.