ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2016
Variations in fat mass contribution to bone mineral density by gender, age, and body mass index: the Korea National Health and Nutrition Examination Survey (KNHANES) 2008-2011.
Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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25 citing papers in PubMed, 34 citations in OpenAlex.
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- Central obesity is more strongly associated with vertebral fractures than general obesity: a cross-sectional study.BMC geriatrics · 2025Article
- Sex-specific associations of fat and lean indices with vertebral fractures.Scientific reports · 2025Article
- The association between relative fat mass (RFM) and lumbar bone density in US adults: Insight from 2011-2018 NHANES.PloS one · 2025Article
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- Osteoporosis in Parkinson's disease and the role of lean body mass: a cross-sectional study in a Brazilian tertiary center.Frontiers in endocrinology · 2024Article
- Association between body fat and bone mineral density in Korean adults: a cohort study.Scientific reports · 2023Article
- Machine learning algorithms for predicting the risk of fracture in patients with diabetes in China.Heliyon · 2023Article
- Identification of three bacterial species associated with increased appendicular lean mass: the HUNT study.Nature communications · 2023Article
- Different associations between waist circumference and bone mineral density stratified by gender, age, and body mass index.BMC musculoskeletal disorders · 2022Article
- A review of menopause nomenclature.Reproductive health · 2022Review
- The Inverse Association of Leg Fat Mass and Osteoporosis in Individuals with Type 2 Diabetes Independent of Lean Mass.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022Article
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- Young cancer survivors have lower bone mineral density compared with healthy controls: a nationwide population-based study in Korea.Scientific reports · 2020Article
- Are body circumferences able to predict strength, muscle mass and bone characteristics in obesity? A preliminary study in women.International journal of medical sciences · 2020Article
- High Body Mass Index and Triglycerides Help Protect against Osteoporosis in Patients with Type 2 Diabetes Mellitus.Journal of diabetes research · 2020Article
- Association between Visceral Fat and Bone Mineral Density in Both Male and Female Patients with Adult Growth Hormone Deficiency.Biochemistry research international · 2020Article
- The risk of eating disorders and bone health in young adults: the mediating role of body composition and fitness.Eating and weight disorders : EWD · 2019Observational
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6 authors at 3 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
unlabelledThe relationship of body composition and bone mineral density is complex and controversial. When classifying Korean population based on gender, age, and body mass index, fat mass had varying contributions to bone mineral density.
introductionThe relationship between body composition and bone mineral density (BMD) is complex, and it is uncertain how components of body mass variably affect BMD.
methodsThis cross-sectional observational study was performed in subjects ≥20 years based on the Korea National Health and Nutrition Examination Survey (KNHANES) 2008 to 2011. Among 17,583 subjects, the mean ages were 49.1 ± 16.0 years (M, n = 7495) and 49.3 ± 16.3 years (F, n = 10,088). Subjects were divided into age groups, either <50 or ≥50 years for males, or menopausal state, either premenopausal or postmenopausal, for females. A further classification used BMI, either <25 or ≥25 kg/m(2). Anthropometric and body composition parameters were compared and evaluated to look for correlations with BMD. Further, appendicular lean mass (ALM), fat mass (FM), fat percentage (FP), and waist circumference (WC) were included for multivariate analysis with BMD, controlling for covariates in each age group and BMI subgroup.
resultsAnthropometric and body composition parameters significantly correlated with BMD in all age groups for both genders. After adjusting for covariates, ALM strongly affected BMD in all age groups for both genders. FM, FP, and WC significantly affected BMD in both age groups of women and in older men, but they did not affect BMD in younger men. Fat indices positively affected BMD of all sites in all non-obese women and in non-obese older men. However, little contribution was found in obese subgroups of both genders and in non-obese younger men.
conclusionConsidering different weights of covariates, ALM strongly contributed to BMD in all gender, age, and BMI groups. On the other hand, fat indices positively affected BMD of both age groups in women and older men with normal BMI, but they showed little contribution to BMD within the same age groups with high BMI or any BMI subgroups of younger men.
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