ArticleCurrent biology : CB2016
Mice Develop Efficient Strategies for Foraging and Navigation Using Complex Natural Stimuli.
Article in Current biology : CB, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers.
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Who cites it
76 citing papers in PubMed.
- Article
- Mouse predation is dependent on a population of POU6F2-positive retinal ganglion cells.iScience · 2026Article
- Article
- Neural dynamics for working memory and evidence integration during olfactory navigation in Drosophila.Nature communications · 2026Article
- Visual uncertainty and task demands shape active sensing strategies in mice.Current biology : CB · 2026Article
- Visual uncertainty and task demands shape active sensing strategies in mice.bioRxiv : the preprint server for biology · 2026Article
- Neuroglial CB1 receptors modulate hippocampal processes in a sex-dependent manner.Biology of sex differences · 2026Article
- Nutritional missed opportunity costs: wild house mice (Mus musculus) consistently consume less preferred food, with implications for control.Pest management science · 2026Article
- Foraging as an ethological framework for neuroscience.Trends in neurosciences · 2025Review
- Neural dynamics for working memory and evidence integration during olfactory navigation inbioRxiv : the preprint server for biology · 2025Article
- Distinct brain regions map olfactory and visual spaces.bioRxiv : the preprint server for biology · 2025Article
- Sex differences in visually guided orienting behavior emerges during adolescence in mice.iScience · 2025Article
- Article
- The 3D Vertical Maze: A new model system for studying the interactions between social and spatial cognition.Journal of neuroscience methods · 2025Article
- Navigation strategies in Caenorhabditis elegans are differentially altered by learning.PLoS biology · 2025Article
- Article
- Information sharing within a social network is key to behavioral flexibility-Lessons from mice tested under seminaturalistic conditions.Science advances · 2025Article
- Octopus track chemosensory plumes to find food.PloS one · 2025Article
- ONIX: a unified open-source platform for multimodal neural recording and perturbation during naturalistic behavior.Nature methods · 2025Article
- Olfactory bulb tracks breathing rhythms and place in freely behaving mice.bioRxiv : the preprint server for biology · 2024Article
16 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors.
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Abstract
The ability to shift between multiple decision-making strategies during natural behavior allows animals to strike a balance between flexibility and efficiency. We investigated odor-guided navigation by mice to understand how decision-making strategies are balanced during a complex natural behavior. Mice navigated to odor sources in an open arena using naturally fluctuating airborne odor cues as their positions were recorded precisely in real time. When mice had limited prior experience of source locations, their search behavior was consistent with a gradient ascent algorithm that utilized directional cues in the plume to navigate to the odor source. Gradient climbing was effective because the arena size allowed animals to conduct their search mainly within the odor plume, with frequent odor contacts. With increased experience, mice shifted their strategy from this flexible, sensory-driven search behavior to a more efficient and stereotyped foraging approach that varied little in response to odor plumes. This study demonstrates that mice use prior knowledge to adaptively balance flexibility and efficiency during complex behavior guided by dynamic natural stimuli.
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