Evidence map›Paper›PMID 27112260›Full record

ReviewThoracic surgery clinics2016

From Diagnosis to Treatment: Clinical Applications of Nanotechnology in Thoracic Surgery.

Christopher S Digesu, Sophie C Hofferberth, Mark W Grinstaff, Yolonda L Colson

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Thoracic surgery clinics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Christopher S DigesuDivision of Thoracic Surgery, Department of Surgery, Brigham and Women's Hospital, 15 Francis St, Boston, MA 02115, USA.
Sophie C HofferberthDivision of Thoracic Surgery, Department of Surgery, Brigham and Women's Hospital, 15 Francis St, Boston, MA 02115, USA.
Mark W GrinstaffDepartment of Biomedical Engineering, Metcalf Science Center, Boston University, SCI 518, 590 Commonwealth Avenue, Boston, MA 02215, USA; Department of Chemistry, Metcalf Science Center, Boston University, SCI 518, 590 Commonwealth Avenue, Boston, MA 02215, USA; Department of Medicine, Metcalf Science Center, Boston University, SCI 518, 590 Commonwealth Avenue, Boston, MA 02215, USA.
Yolonda L ColsonDivision of Thoracic Surgery, Department of Surgery, Brigham and Women's Hospital, 15 Francis St, Boston, MA 02115, USA; Division of Thoracic Surgery, Brigham and Women's Hospital, Harvard Medical School, 15 Francis St, Boston, MA 02155, USA. Electronic address: ycolson@partners.org.
Brigham and Women's Hospital · USBoston University · USHarvard University · US

Funding

ADVANCED TRAINING IN SURGICAL ONCOLOGYT32CA009535 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI BUENO, RAPHAEL · 1985 to 2015
$3.5M
Boston University Cross-Disciplinary Training in Nanotechnology for CancerR25CA153955 · NCI · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI FALLER, DOUGLAS V, GOLDBERG, BENNETT B · 2010 to 2014
$2.1M
NIR Imaging of Sentinel Nodes in Lung Cancer: Finding MicrometastasesR01CA131044 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI COLSON, YOLONDA L · 2008 to 2011
$1.5M
Flexible, Conformal, Polymeric Films for Lung Resection MarginsR01CA149561 · NCI · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI COLSON, YOLONDA L, GRINSTAFF, MARK W. · 2011 to 2014
$1.4M
NCI NIH HHS R01 CA131044NCI NIH HHS R01 CA149561NCI NIH HHS R25 CA153955NCI NIH HHS T32 CA009535
6 · The paper itself

Abstract

Nanotechnology is an emerging field with potential as an adjunct to cancer therapy, particularly thoracic surgery. Therapy can be delivered to tumors in a more targeted fashion, with less systemic toxicity. Nanoparticles may aid in diagnosis, preoperative characterization, and intraoperative localization of thoracic tumors and their lymphatics. Focused research into nanotechnology's ability to deliver both diagnostics and therapeutics has led to the development of nanotheranostics, which promises to improve the treatment of thoracic malignancies through enhanced tumor targeting, controlled drug delivery, and therapeutic monitoring. This article reviews nanoplatforms, their unique properties, and the potential for clinical application in thoracic surgery.

Indexed as

HumansLung NeoplasmsNanotechnologyThoracic SurgeryThoracic Surgical ProceduresLung cancerNanotechnologyNanotheranosticsThoracic surgery

Identifiers

PMID27112260
PMCPMC4851727
OpenAlexW2343084804

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.