Evidence map›Paper›PMID 27112222›Full record

ReviewOphthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)2016

The fundus photo has met its match: optical coherence tomography and adaptive optics ophthalmoscopy are here to stay.

Jessica I W Morgan

Open access · bronzeAbstract readReview
In one paragraph

Review in Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 60 citations in OpenAlex.

  1. Review
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  3. Review
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  5. Retinal Sensitivity in Comparison to Cone Density in Choroideremia.Investigative ophthalmology & visual science · 2024
    Article
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  9. Review
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  16. Review
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  20. A 2-Year Longitudinal Study of Normal Cone Photoreceptor Density.Investigative ophthalmology & visual science · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Jessica I W MorganDepartment of Ophthalmology, Scheie Eye Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA.
University of Pennsylvania · US

Funding

Scientific TransparencyP30EY001583 · NEI · UNIVERSITY OF PENNSYLVANIA · PI Qi N Cui · 1985 to 2026
$19.5M
Platform Technologies for Microscopic Retinal Imaging: Development & TranslationU01EY025477 · NEI · STANFORD UNIVERSITY · PI DUBRA, ALFREDO · 2015 to 2019
$4.4M
Human Connectomes for Low Vision, Blindness, and Sight RestorationU01EY025864 · NEI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI AGUIRRE, GEOFFREY KARL, PATEL, VIVEK R. · 2015 to 2018
$4.0M
NEI NIH HHS P30 EY001583NEI NIH HHS U01 EY025477NEI NIH HHS U01 EY025864
6 · The paper itself

Abstract

purposeOver the past 25 years, optical coherence tomography (OCT) and adaptive optics (AO) ophthalmoscopy have revolutionised our ability to non-invasively observe the living retina. The purpose of this review is to highlight the techniques and human clinical applications of recent advances in OCT and adaptive optics scanning laser/light ophthalmoscopy (AOSLO) ophthalmic imaging. RECENT

findingsOptical coherence tomography retinal and optic nerve head (ONH) imaging technology allows high resolution in the axial direction resulting in cross-sectional visualisation of retinal and ONH lamination. Complementary AO ophthalmoscopy gives high resolution in the transverse direction resulting in en face visualisation of retinal cell mosaics. Innovative detection schemes applied to OCT and AOSLO technologies (such as spectral domain OCT, OCT angiography, confocal and non-confocal AOSLO, fluorescence, and AO-OCT) have enabled high contrast between retinal and ONH structures in three dimensions and have allowed in vivo retinal imaging to approach that of histological quality. In addition, both OCT and AOSLO have shown the capability to detect retinal reflectance changes in response to visual stimuli, paving the way for future studies to investigate objective biomarkers of visual function at the cellular level. Increasingly, these imaging techniques are being applied to clinical studies of the normal and diseased visual system. SUMMARY: Optical coherence tomography and AOSLO technologies are capable of elucidating the structure and function of the retina and ONH noninvasively with unprecedented resolution and contrast. The techniques have proven their worth in both basic science and clinical applications and each will continue to be utilised in future studies for many years to come.

Indexed as

Optics and PhotonicsFundus OculiHumansOphthalmoscopyRetinaTomography, Optical Coherenceadaptive optics ophthalmoscopyangiographyoptical coherence tomographyphotoreceptorsretinal and choroidal vasculaturescanning laser ophthalmoscopy

Identifiers

PMID27112222
PMCPMC4963017
OpenAlexW2343943864

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.