Evidence map›Paper›PMID 27112144›Full record

ArticleClinical rheumatology2016

Hearing impairment in patients with rheumatoid arthritis: association with anti-citrullinated protein antibodies.

Fabrício Silva Lobo, Mario Orlando Dossi, Lígia Batista, Márcia Midori Shinzato

Abstract read
PubMed Publisher
In one paragraph

Article in Clinical rheumatology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 3 pooled it
1.6field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. The Effect of Rheumatoid Arthritis on Middle and Inner Ear Functions.Turkish archives of otorhinolaryngology · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Hearing Function in Adults with Rheumatoid Arthritis: A Scoping Review for Preventive Audiology Planning.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2022
    Article
  12. Article
  13. Article
  14. Hearing status in patients with rheumatoid arthritis.Caspian journal of internal medicine · 2019
    Article
  15. Article
  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Fabrício Silva LoboDepartment of Otolaryngology, University Hospital, Grande Dourados University, Rua Gerônimo Marques Matos, 558, CEP:79823-855, Dourados, MS, Brazil.
Mario Orlando DossiDepartment of Otolaryngology, University Hospital, Grande Dourados University, Rua Gerônimo Marques Matos, 558, CEP:79823-855, Dourados, MS, Brazil.
Lígia BatistaDepartment of Otolaryngology, University Hospital, Grande Dourados University, Rua Gerônimo Marques Matos, 558, CEP:79823-855, Dourados, MS, Brazil.
Márcia Midori ShinzatoFaculty of Health Science, Grande Dourados University, 364, Rodovia Dourados-Itahum, Km 12, CEP:79804-970, Dourados, MS, Brazil. marciashinzato@ufgd.edu.br.
Universidade Federal da Grande Dourados · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It has been suggested that hearing impairment (HI) is one of the extra-articular features of rheumatoid arthritis (RA). Nevertheless, the prevalence and nature of HI in RA is still uncertain. The objectives were to study hearing function in patients with RA using audiometric tests and to examine whether HI correlates with autoantibodies. Hearing functions were investigated in 43 consecutive RA patients and 23 control subjects (less than 60 years old). Their sera were evaluated for the presence of rheumatoid factor (RF), anti-cyclic citrullinated peptide (anti-CCP), and anti-mutated citrullinated vimentin (anti-MCV) antibodies. HI was observed in 46.5 % of RA patients and in 30.4 % of control subjects, p = 0.32. HI was characterized as sensorineural in 80 and 85.7 % of RA patients and control subjects with HI, respectively, p = 1.00. RA patients had a worse hearing threshold for air conduction at 6 kHz in the right ear (p = 0.019) and had a decreased amplitude of otoacoustic emissions (OAEs) at 2 kHz bilaterally (p = 0.04) compared with control subjects. In the RA group, patients with and without HI were 80 and 34.78 % anti-CCP positive, respectively, p = 0.008. RA patients with and without HI were 85 and 43.48 % anti-MCV positive, respectively, p = 0.013. HI in RA patients was mainly sensorineural and was associated with anti-CCP and anti-MCV antibodies.

Indexed as

AdultArthritis, RheumatoidAutoantibodiesFemaleHearing LossHumansMaleMiddle AgedPeptides, CyclicRheumatoid FactorVimentinAutoantibodiescyclic citrullinated peptidePeptides, CyclicRheumatoid FactorVimentinAnti-citrullinated protein antibodiesAutoantibodiesHearing lossRheumatoid arthritis

Identifiers

PMID27112144
OpenAlexW2344144854

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.