ArticleParasites & vectors2016
Experimental transmission of Babesia microti by Rhipicephalus haemaphysaloides.
Article in Parasites & vectors, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Infection rates, species diversity, and distribution of zoonotic Babesia parasites in ticks: a global systematic review and meta-analysis.Parasitology research · 2022Pooled it
- Morphological and Molecular Characterization of Tick Species Infesting Cattle in South Africa.Veterinary sciences · 2024Article
- Disruption of bacterial interactions and community assembly in Babesia-infected Haemaphysalis longicornis following antibiotic treatment.BMC microbiology · 2024Article
- Nucleic Acid Prevalence of ZoonoticTropical medicine and infectious disease · 2023Review
- Experimental Infection of Ticks: An Essential Tool for the Analysis ofPathogens (Basel, Switzerland) · 2021Review
- Detection of Multiple Intracellular Bacterial Pathogens inPathogens (Basel, Switzerland) · 2021Article
- Challenges in Tick-Borne Pathogen Detection: The Case forPathogens (Basel, Switzerland) · 2021Review
- A cysteine protease of Babesia microti and its interaction with tick cystatins.Parasitology research · 2020Article
- Detection of novel piroplasmid species and Babesia microti and Theileria orientalis genotypes in hard ticks from Tengchong County, Southwest China.Parasitology research · 2020Article
- Tissue Localization and Variation of Major Symbionts in Haemaphysalis longicornis, Rhipicephalus haemaphysaloides, and Dermacentor silvarum in China.Applied and environmental microbiology · 2018Article
- Effects of antibiotic treatment on the fecundity of Rhipicephalus haemaphysaloides ticks.Parasites & vectors · 2018Article
- Molecular evidence for the transovarial passage of Babesia gibsoni in Haemaphysalis hystricis (Acari: Ixodidae) ticks from Taiwan: a novel vector for canine babesiosis.Parasites & vectors · 2018Article
- Endosymbionts Alter Larva-to-Nymph Transstadial Transmission ofFrontiers in microbiology · 2018Article
- Evaluation on Infectivity ofFrontiers in microbiology · 2017Article
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5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundHuman babesiosis is considered an emerging threat in China. Dozens of human infections with Babesia microti have been reported recently, especially in southern China. However, the transmission vectors of this parasite in these areas are not well understood. Rhipicephalus haemaphysaloides, which is one of the dominant tick species in southern China, is a major vector of bovine babesiosis in China. However, whether this tick has the potential to transmit B. microti has not been tested. The present study experimentally investigated the transmission competence of B. microti through R. haemaphysaloides ticks.
methodsLarvae and nymphs of R. haemaphysaloides ticks were fed on laboratory mice infected by B. microti. The infection was detected by PCR at 4 weeks post-molting. BALB/c and NOD/SCID mice were infested by nymphs molting from larvae that ingested the blood of infective mice, and blood samples were then analyzed by PCR.
resultsExperimental transstadial transmission of R. haemaphysaloides for B. microti was proved in both the larvae to nymph and the nymph to adult transstadial routes. The positive rate of B. microti was 43.8% in nymphs developed from larvae consumed infected mice and 96.7% in adults developed from nymphs exposed to positive mice. Among the mice infested by infective nymphs, B. microti was detected in 16.7% (2/12) of the BALB/c mice and in all of the NOD/SCID (6/6). However, the parasite was not observed to persist beyond more than one molt, and transovarial transmission did not occur.
conclusionsThis is the first study to demonstrate that B. microti can be transmitted artificially by R. haemaphysaloides. This tick species might be a potential vector of human babesiosis in southern China, which represents a public health concern.
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