ArticleACS applied materials & interfaces2016
Gelatin Microgel Incorporated Poly(ethylene glycol)-Based Bioadhesive with Enhanced Adhesive Property and Bioactivity.
Article in ACS applied materials & interfaces, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
36 citing papers in PubMed.
- Expandable Nanocomposite Shape-Memory Hemostat for the Treatment of Noncompressible Hemorrhage.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Dopamine-Conjugated Methacrylated Gelatin Hydrogel-Physical, Mechanical, and Biological Properties.Gels (Basel, Switzerland) · 2025Article
- Accelerated dermal wound healing in diabetic mice by a HJournal of materials chemistry. B · 2025Article
- Laponite nanoclay loaded microgel suspensions as supportive matrices for osteogenesis.Advanced nanobiomed research · 2024Article
- Injectable Nanoengineered Adhesive Hydrogel for Treating Enterocutaneous Fistulas.Acta biomaterialia · 2024Article
- Enhancing the interfacial binding strength between modular stretchable electronic components.National science review · 2023Review
- Article
- pH Responsive Antibacterial Hydrogel Utilizing Catechol-Boronate Complexation Chemistry.Chemical engineering journal (Lausanne, Switzerland : 1996) · 2022Article
- Cohesion mechanisms for bioadhesives.Bioactive materials · 2022Review
- Droplet microfluidic devices for organized stem cell differentiation into germ cells: capabilities and challenges.Biophysical reviews · 2021Review
- Catechol-Based Antimicrobial Polymers.Molecules (Basel, Switzerland) · 2021Review
- Mussel-inspired biocompatible polydopamine/carboxymethyl cellulose/polyacrylic acid adhesive hydrogels with UV-shielding capacity.Cellulose (London, England) · 2021Article
- In vivo performance of a bilayer wrap to prevent abdominal adhesions.Acta biomaterialia · 2020Article
- Gelatin Matrices for Growth Factor Sequestration.Trends in biotechnology · 2020Review
- Enhancement performance of application mussel-biomimetic adhesive primer for dentin adhesives.RSC advances · 2020Article
- Correlating the mass and mechanical property changes during the degradation of PEG-based adhesive.Journal of applied polymer science · 2020Article
- Multifunctional Biomedical Adhesives.Advanced healthcare materials · 2019Review
- Development of an Injectable Nitric Oxide Releasing Poly(ethylene) Glycol-Fibrin Adhesive Hydrogel.ACS biomaterials science & engineering · 2019Article
- Injectable Macroporous Hydrogel Formed by Enzymatic Cross-Linking of Gelatin Microgels.ACS applied bio materials · 2018Article
- Hydrogel Biomaterials for Stem Cell Microencapsulation.Polymers · 2018Review
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Up to 7.5 wt % of chemically cross-linked gelatin microgel was incorporated into dopamine-modified poly(ethylene glycol) (PEGDM) adhesive to simultaneously improve the material property and bioactivity of the PEG-based bioadhesive. Incorporation of gelatin microgel reduced cure time while it increased the elastic modulus and cross-linking density of the adhesive network. Most notably, the loss modulus values for microgel-containing adhesive were an order of magnitude higher when compared to microgel-free control. This drastic increase in the viscous dissipation ability of the adhesive is attributed to the introduction of reversible physical bonds into the adhesive network with the incorporation of the gelatin microgel. Additionally, incorporation of the microgel increased the adhesive properties of PEGDM by 1.5- to 2-fold. From in vitro cell culture studies, the composite adhesive is noncytotoxic and the incorporation of microgels provided binding site for promoting fibroblast attachment and viability. The subcutaneous implantation study indicated that the microgel-containing PEGDM adhesive is biocompatible and the incorporated microgels provided pockets for rapid cellular infiltration. Gelatin microgel incorporation was demonstrated to be a facile method to simultaneously enhance the adhesive property and the bioactivity of PEG-based adhesive.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.