ArticleArthritis care & research2016
Quantifying Temporomandibular Joint Synovitis in Children With Juvenile Idiopathic Arthritis.
Article in Arthritis care & research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- The Diagnosis and Treatment of Rheumatoid and Juvenile Idiopathic Arthritis of the Temporomandibular Joint.Deutsches Arzteblatt international · 2022Pooled it
- Controversial Aspects of Diagnostics and Therapy of Arthritis of the Temporomandibular Joint in Rheumatoid and Juvenile Idiopathic Arthritis-An Analysis of Evidence- and Consensus-Based Recommendations Based on an Interdisciplinary Guideline Project.Journal of clinical medicine · 2022Article
- The Role of Ultrasound in Temporomandibular Joint Disorders: An Update and Future Perspectives.Frontiers in medicine · 2022Review
- Initial radiological signs of dentofacial deformity in juvenile idiopathic arthritis.Scientific reports · 2021Article
- Concerted Actions by PIICP, CTXII, and TNF-α in Patients with Juvenile Idiopathic Arthritis.Biomolecules · 2021Article
- Comprehensive Management of Rheumatic Diseases Affecting the Temporomandibular Joint.Diagnostics (Basel, Switzerland) · 2021Review
- Prosthetic temporomandibular joint reconstruction in a cohort of adolescent females with juvenile idiopathic arthritis.Pediatric rheumatology online journal · 2020Article
- Contrast-enhanced MRI compared to direct joint visualization at arthroscopy in pediatric patients with suspected temporomandibular joint synovitis.Pediatric radiology · 2019Article
- Developing a reference MRI database for temporomandibular joints in healthy children and adolescents.Pediatric radiology · 2018Article
- Imaging of temporomandibular joint abnormalities in juvenile idiopathic arthritis with a focus on developing a magnetic resonance imaging protocol.Pediatric radiology · 2018Review
- Juvenile idiopathic arthritis - the role of imaging from a rheumatologist's perspective.Pediatric radiology · 2018Review
- Temporomandibular joint arthritis in juvenile idiopathic arthritis, now what?Pediatric rheumatology online journal · 2018Review
- Temporomandibular joint atlas for detection and grading of juvenile idiopathic arthritis involvement by magnetic resonance imaging.Pediatric radiology · 2018Review
- Normal magnetic resonance appearances of the temporomandibular joints in children and young adults aged 2-18 years.Pediatric radiology · 2018Article
- Defining the normal appearance of the temporomandibular joints by magnetic resonance imaging with contrast: a comparative study of children with and without juvenile idiopathic arthritis.Pediatric rheumatology online journal · 2018Article
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveJuvenile idiopathic arthritis (JIA) frequently affects the temporomandibular joints (TMJs) and is often undetected by history, examination, and plain imaging. Qualitative assessment of gadolinium-enhanced magnetic resonance images (MRIs) is currently the standard for diagnosis of TMJ synovitis associated with JIA. The purpose of this study is to apply a quantitative analysis of synovial enhancement to MRIs of patients with and without JIA to establish a disease threshold and sensitivity and specificity for the technique.
methodsThis is a retrospective case-control study of children (age ≤16 years) who had MRIs with gadolinium including the TMJs. Subjects were divided into a JIA group and a control group. From a coronal T1-weighted image, a ratio (enhancement ratio [ER]) of the average pixel intensity within three 0.2-mm
resultsThere were 187 and 142 TMJs included in the JIA and control groups, respectively. An ER threshold of 1.55 had a sensitivity and specificity for detecting synovitis of 91% and 96%, respectively. The inter- and intraexaminer reliability was excellent.
conclusionCalculating a ratio of pixel intensity between the TMJ synovium and the longus capitis muscle is a reliable way to quantify synovial enhancement. An ER of 1.55 differentiates normal TMJs from those affected by inflammatory arthritis.
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