Evidence map›Paper›PMID 27110812›Full record

ReviewViruses2016

Molecular Insights into Crimean-Congo Hemorrhagic Fever Virus.

Marko Zivcec, Florine E M Scholte, Christina F Spiropoulou, Jessica R Spengler, Éric Bergeron

Open access · goldAbstract readReview
In one paragraph

Review in Viruses, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers.

0numbers the graph read from it
0cells of the map it votes in
90citing papers in PubMed
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

90 citing papers in PubMed, 139 citations in OpenAlex.

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30 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Marko ZivcecViral Special Pathogens Branch, Division of High Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. mzivcec@cdc.gov.
Florine E M ScholteViral Special Pathogens Branch, Division of High Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. kyj7@cdc.gov.
Christina F SpiropoulouViral Special Pathogens Branch, Division of High Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. ccs8@cdc.gov.
Jessica R SpenglerViral Special Pathogens Branch, Division of High Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. wsk7@cdc.gov.
Éric BergeronViral Special Pathogens Branch, Division of High Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. ebergeron@cdc.gov.
Centers for Disease Control and Prevention · US

Funding

Origin of the innate immunity suppression caused by nairovirus' protease activityR01AI109008 · NIAID · UNIVERSITY OF GEORGIA · PI PEGAN, SCOTT DUSAN · 2014 to 2018
$1.6M
NIAID NIH HHS R01 AI109008NIAID NIH HHS R01AI109008
6 · The paper itself

Abstract

Crimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne pathogen that causes high morbidity and mortality. Efficacy of vaccines and antivirals to treat human CCHFV infections remains limited and controversial. Research into pathology and underlying molecular mechanisms of CCHFV and other nairoviruses is limited. Significant progress has been made in our understanding of CCHFV replication and pathogenesis in the past decade. Here we review the most recent molecular advances in CCHFV-related research, and provide perspectives on future research.

Indexed as

Gene Expression Regulation, ViralGenome, ViralGenomicsHemorrhagic Fever, CrimeanHemorrhagic Fever Virus, Crimean-CongoHumansTranscription, GeneticViral ProteinsVirus InternalizationVirus ReleaseVirus ReplicationViral ProteinsCrimean-Congo hemorrhagic feverpathogenesisreverse geneticstick-borne virusviral hemorrhagic fever

Identifiers

PMID27110812
PMCPMC4848600
OpenAlexW2340920240

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.