Evidence map›Paper›PMID 27110595›Full record

ArticlemSphere2016

A Gammaherpesvirus Noncoding RNA Is Essential for Hematogenous Dissemination and Establishment of Peripheral Latency.

Emily R Feldman, Mehmet Kara, Lauren M Oko, Katrina R Grau, Brian J Krueger, Junjie Zhang, Pinghui Feng, Linda F van Dyk, Rolf Renne, Scott A Tibbetts

Abstract read
In one paragraph

Article in mSphere, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Evaluation of immune sensor responses to a viral small noncoding RNA.Frontiers in cellular and infection microbiology · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Deletion of Murine Gammaherpesvirus GeneJournal of virology · 2020
    Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Emily R FeldmanDepartment of Molecular Genetics and Microbiology and UF Health Cancer Center, College of Medicine, University of Florida, Gainesville, Florida, USA.
Mehmet KaraDepartment of Molecular Genetics and Microbiology and UF Health Cancer Center, College of Medicine, University of Florida, Gainesville, Florida, USA.
Lauren M OkoDepartment of Microbiology and Immunology, University of Colorado School of Medicine, Aurora, Colorado, USA.
Katrina R GrauDepartment of Molecular Genetics and Microbiology and UF Health Cancer Center, College of Medicine, University of Florida, Gainesville, Florida, USA.
Brian J KruegerDepartment of Molecular Genetics and Microbiology and UF Health Cancer Center, College of Medicine, University of Florida, Gainesville, Florida, USA.
Junjie ZhangDepartment of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Pinghui FengDepartment of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Linda F van DykDepartment of Microbiology and Immunology, University of Colorado School of Medicine, Aurora, Colorado, USA.
Rolf RenneDepartment of Molecular Genetics and Microbiology and UF Health Cancer Center, College of Medicine, University of Florida, Gainesville, Florida, USA.
Scott A TibbettsDepartment of Molecular Genetics and Microbiology and UF Health Cancer Center, College of Medicine, University of Florida, Gainesville, Florida, USA.

Funding

BASIC MICROBIOLOGY &INFECTIOUS DISEASEST32AI007110 · NIAID · UNIVERSITY OF FLORIDA · PI Stephanie M Karst · 1985 to 2026
$4.3M
Targeting an immune kinase to purge KSHV latent infectionR01DE026003 · NIDCR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CHEN, CASEY, ZHANG, CHAO · 2016 to 2020
$3.4M
Studying the role of KSHV-encoded miRNAsR01CA119917 · NCI · UNIVERSITY OF FLORIDA · PI RENNE, ROLF F · 2008 to 2017
$3.2M
Proviral Roles of an Innate Immune PathwayR01DE021445 · NIDCR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI FENG, PINGHUI · 2011 to 2017
$2.5M
Role of MHV68 miRNAs in latencyand pathogenesisR01AI108407 · NIAID · UNIVERSITY OF FLORIDA · PI TIBBETTS, SCOTT A. · 2015 to 2019
$2.0M
Non-coding RNAs in Gammaherpesvirus Infection and DiseaseR01AI121300 · NIAID · UNIVERSITY OF COLORADO DENVER · PI VAN DYK, LINDA F. · 2016 to 2019
$1.5M
Cyclin requirements in gammaherpesvirus infection and diseaseR01CA168558 · NCI · UNIVERSITY OF COLORADO DENVER · PI VAN DYK, LINDA F. · 2012 to 2016
$1.5M
NCI NIH HHS R01 CA119917NCI NIH HHS R01 CA168558NIAID NIH HHS R01 AI108407NIAID NIH HHS R01 AI121300NIAID NIH HHS T32 AI007110NIDCR NIH HHS R01 DE021445NIDCR NIH HHS R01 DE026003
6 · The paper itself

Abstract

Recent intense investigations have uncovered important functions for a diverse array of novel noncoding RNA (ncRNA) species, including microRNAs (miRNAs) and long noncoding RNAs. Not surprisingly, viruses from multiple families have evolved to encode their own regulatory RNAs; however, the specific IMPORTANCE: Noncoding RNAs (ncRNAs) represent an intriguing and diverse class of molecules that are now recognized for their participation in a wide array of cellular processes. Viruses from multiple families have evolved to encode their own such regulatory RNAs; however, the specific

Indexed as

disseminationherpesviruseslatencymiRNAnoncoding RNATMERviral pathogenesis

Identifiers

PMID27110595
PMCPMC4838037

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.