ArticleCase reports in medicine2016
Thyroid Carcinoma Showing Thymic-Like Differentiation Causing Fracture of the Trachea.
Article in Case reports in medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 12 citations in OpenAlex.
- Coexistence of intrathyroid thymic carcinoma and papillary thyroid carcinoma: a case report and literature review.Frontiers in oncology · 2024Article
- TOETVA: a single surgeon's learning curve and a case report of CASTLE thyroid tumor.Langenbeck's archives of surgery · 2023Article
- Thyroid Carcinoma Showing Thymus-like Differentiation (CASTLE): A Case Report.Life (Basel, Switzerland) · 2022Article
- Recurrence of carcinoma showing thymus-like differentiation (CASTLE) involving the thyroid gland.Thyroid research · 2021Article
- Thyroid Carcinoma Showing Thymus-Like Differentiation (CASTLE) with Tracheal Invasion: A Case Report.The American journal of case reports · 2019Review
- The 'CASTLE' tumour: An extremely rare presentation of a thyroid malignancy. A case report.Annals of medicine and surgery (2012) · 2019Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Thyroid carcinoma showing thymic-like differentiation (CASTLE) comprises a rare neoplasm of the thyroid gland which arises from ectopic thymic tissue or remnants of brachial pouches. CASTLE is regarded as an indolent neoplasm with a favorable prognosis, irrespective of its metastatic potential. Diagnosis is difficult as clinicopathological features have not been yet well-defined. Radiological findings are not specific and only immunohistochemical positivity for CD5 and CD117 staining is highly suggestive of CASTLE. Despite lack of universally accepted treatment recommendations, the mainstay treatment includes thyroidectomy and systematic lymph node dissection. We report a case of CASTLE tumour with very uncommon characteristics developed in a 76-year-old man, who presented with rapidly deteriorating dyspnea and severe cough, resulting in respiratory failure. At surgery, a suspicious looking tumour arising from the upper pole of the right lobe of the thyroid gland, surrounding the trachea and displacing the right common carotid artery, was identified. The patient underwent en bloc resection of the tumour with the thyroid gland and regional lymph node dissection. This is the first reported case of CASTLE causing tracheal ring fracture.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.