ArticleInternational journal of chronic obstructive pulmonary disease2016
Continuous quantitative measurement of the proximal airway dimensions and lung density on four-dimensional dynamic-ventilation CT in smokers.
Article in International journal of chronic obstructive pulmonary disease, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 36 citations in OpenAlex.
- Investigation into the utility of ultra-high-resolution mode on dynamic-ventilation computed tomography using sponge phantoms.Scientific reports · 2025Article
- Multi-modal evaluation of respiratory diaphragm motion in chronic obstructive pulmonary disease using MRI series and CT images.Japanese journal of radiology · 2024Article
- Low-Dose Whole-Chest Dynamic CT for the Assessment of Large Airway Collapsibility in Patients with Suspected Tracheobronchial Instability.Radiology. Cardiothoracic imaging · 2024Article
- The utility of quantitative computed tomography in cohort studies of chronic obstructive pulmonary disease: a narrative review.Journal of thoracic disease · 2023Review
- Quantitative analyzes of the variability in airways via four-dimensional dynamic ventilation CT in patients with chronic obstructive pulmonary disease: correlation with spirometry data and severity of airflow limitation.Journal of thoracic disease · 2023Article
- Quantitative measurements of emphysema in ultra-high resolution computed tomography using model-based iterative reconstruction in comparison to that using hybrid iterative reconstruction.Physical and engineering sciences in medicine · 2022Article
- Quantitative analysis of changes in lung density by dynamic chest radiography in association with CT values: a virtual imaging study and initial clinical corroboration.Radiological physics and technology · 2022Article
- Dynamic chest radiography: clinical validation of ventilation and perfusion metrics derived from changes in radiographic lung density compared to nuclear medicine imaging.Quantitative imaging in medicine and surgery · 2021Article
- Assessment of pleural invasion and adhesion of lung tumors with dynamic chest radiography: A virtual clinical imaging study.Medical physics · 2021Article
- Difference in Local Lung Movement During Tidal Breathing Between COPD Patients and Asthma Patients Assessed by Four-dimensional Dynamic-ventilation CT Scan.International journal of chronic obstructive pulmonary disease · 2020Article
- Quantitative Emphysema Measurement On Ultra-High-Resolution CT Scans.International journal of chronic obstructive pulmonary disease · 2019Article
- Quantitative assessment of airway and parenchymal components of chronic obstructive pulmonary disease using thin-section helical computed tomography.Polish journal of radiology · 2019Article
- Computed tomography trachea volumetry in patients with scleroderma: Association with clinical and functional findings.PloS one · 2018Article
- 3D-measurement of tracheobronchial angles on inspiratory and expiratory chest CT in COPD: respiratory changes and correlation with airflow limitation.International journal of chronic obstructive pulmonary disease · 2018Article
- Hyperinflated lungs compress the heart during expiration in COPD patients: a new finding on dynamic-ventilation computed tomography.International journal of chronic obstructive pulmonary disease · 2017Article
- Asynchrony in respiratory movements between the pulmonary lobes in patients with COPD: continuous measurement of lung density by 4-dimensional dynamic-ventilation CT.International journal of chronic obstructive pulmonary disease · 2017Article
- Strain measurement on four-dimensional dynamic-ventilation CT: quantitative analysis of abnormal respiratory deformation of the lung in COPD.International journal of chronic obstructive pulmonary diseaseArticle
- Continuous quantitative measurement of the main bronchial dimensions and lung density in the lateral position by four-dimensional dynamic-ventilation CT in smokers and COPD patients.International journal of chronic obstructive pulmonary diseaseArticle
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeFour-dimensional dynamic-ventilation computed tomography (CT) imaging demonstrates continuous movement of the airways and lungs, which cannot be depicted with conventional CT. We aimed to investigate continuous changes in lung density and airway dimensions and to assess the correlation with spirometric values in smokers. MATERIALS AND
methodsThis retrospective study was approved by the Institutional Review Board, and informed consent was waived. Twenty-one smokers including six patients with COPD underwent four-dimensional dynamic-ventilation CT during free breathing (160 mm in length). The mean lung density (MLD) of the scanned lung and luminal areas (Ai) of fixed points in the trachea and the right proximal bronchi (main bronchus, upper bronchus, bronchus intermedius, and lower bronchus) were continuously measured. Concordance between the time curve of the MLD and that of the airway Ai values was expressed by cross-correlation coefficients. The associations between these quantitative measurements and the forced expiratory volume in 1 second/forced vital capacity (FEV1/FVC) values were assessed by Spearman's rank correlation analysis.
resultsOn the time curve for the MLD, the Δ-MLD1.05 values between the peak inspiratory frame to the later third frame (1.05 seconds later) were strongly correlated with the FEV1/FVC (ρ=0.76, P<0.0001). The cross-correlation coefficients between the airway Ai and MLD values were significantly correlated with the FEV1/FVC (ρ=-0.56 to -0.66, P<0.01), except for the right upper bronchus. This suggested that the synchrony between the airway and lung movement was lost in patients with severe airflow limitation.
conclusionRespiratory changes in the MLD and synchrony between the airway Ai and the MLD measured with dynamic-ventilation CT were correlated with patient's spirometric values.
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