Evidence map›Paper›PMID 27109286›Full record

ArticleOral diseases2016

Viral infections associated with oral cancers and diseases in the context of HIV: a workshop report.

D J Speicher, V Ramirez-Amador, D P Dittmer, J Webster-Cyriaque, M T Goodman, A-B Moscicki

Open access · bronzeAbstract readConference Proceedings
In one paragraph

Article in Oral diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 3 countries.

D J SpeicherMolecular Basis of Disease Research Program, Menzies Health Institute Queensland, Griffith University, Gold Coast, Queensland, Australia.
V Ramirez-AmadorHealth Care Department, Universidad Autónoma Metropolitana-Xochimilco, México City, Mexico.
D P DittmerDepartment of Microbiology and Immunology School of Medicine, University of North Carolina, Chapel Hill, North Carolina, USA.
J Webster-CyriaqueDepartment of Microbiology and Immunology School of Medicine, University of North Carolina, Chapel Hill, North Carolina, USA.
M T GoodmanCancer Prevention and Control, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
A-B MoscickiDavid Geffen, School of Medicine, University of California-Los Angeles, Los Angeles, California, USA.
University of North Carolina at Chapel Hill · USCedars-Sinai Medical Center · USGriffith University · AUUniversidad Autónoma Metropolitana · MXUniversity of California, Los Angeles · US

Funding

ART Modulation of Viral Pathogenesis in Oral EpitheliaR01DE018304 · NIDCR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DITTMER, DIRK P · 2007 to 2025
$6.9M
Innate Immunity and KSHVR01DE018281 · NIDCR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAMANIA, BLOSSOM A · 2007 to 2016
$3.5M
Targeting the epigenome of gammaherpesviruses in oral diseaseR01DE023946 · NIDCR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAMANIA, BLOSSOM A, DITTMER, DIRK P · 2013 to 2017
$2.3M
NIDCR NIH HHS R01 DE018281NIDCR NIH HHS R01 DE018304NIDCR NIH HHS R01 DE023946
6 · The paper itself

Abstract

Human herpesviruses (HHVs) and human papillomavirus (HPV) are common in the general population and, in immunocompetent people, are mostly carried asymptomatically. However, once an individual becomes immunocompromised by age, illness or HIV infection these dormant viruses can manifest and produce disease. In HIV-positive patients, there is an increased risk of disease caused by HHVs and HPV infections and cancers caused by the oncoviruses Epstein-Barr Virus, HHV-8 and HPV. This workshop examined four questions regarding the viruses associated with oral cancers and disease in the HIV-positive and -negative populations, the immune response, and biomarkers useful for accurate diagnostics of these infections and their sequalae. Each presenter identified a number of key areas where further research is required.

Indexed as

BiomarkersCoinfectionEpstein-Barr Virus InfectionsHerpesvirus 8, HumanHIV InfectionsHumansMouth DiseasesMouth NeoplasmsOropharyngeal NeoplasmsPapillomavirus InfectionsSarcoma, KaposiBiomarkersbiomarkersHIV infectionhuman herpesvirushuman papillomavirusimmune responseoncovirusesoral cancer

Identifiers

PMID27109286
PMCPMC5590239
OpenAlexW2343409103

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.