SynthesisJournal of perinatology : official journal of the California Perinatal Association2016
Home-based neonatal care by community health workers for preventing mortality in neonates in low- and middle-income countries: a systematic review.
Synthesis in Journal of perinatology : official journal of the California Perinatal Association, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 7 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
55 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Effect of antenatal care on low birth weight: a systematic review and meta-analysis in Africa, 2022.Frontiers in public health · 2023Pooled it
- Community Health Worker Impact on Knowledge, Antenatal Care, And Birth Outcomes: A Systematic Review.Maternal and child health journal · 2022Pooled it
- The effect of antenatal care on perinatal outcomes in Ethiopia: A systematic review and meta-analysis.PloS one · 2021Pooled it
- Cognitive and motor outcomes in children born low birth weight: a systematic review and meta-analysis of studies from South Asia.BMC pediatrics · 2019Pooled it
- Community health volunteers could help improve access to and use of essential health services by communities in LMICs: an umbrella review.Health policy and planning · 2018Pooled it
- What do we know about community-based health worker programs? A systematic review of existing reviews on community health workers.Human resources for health · 2018Pooled it
- What is the result of vaginal cleansing with chlorhexidine during labour on maternal and neonatal infections? A systematic review of randomised trials with meta-analysis.BMC pregnancy and childbirth · 2018Pooled it
- Effect of home-based newborn care on neonatal and infant mortality: a cluster randomised trial in India.BMJ global health · 2020Trial
- Testing a home-based model of care using misoprostol for prevention and treatment of postpartum hemorrhage: results from a randomized placebo-controlled trial conducted in Badakhshan province, Afghanistan.Reproductive health · 2020Trial
- Effectiveness of an action-oriented educational intervention in ensuring long term improvement of knowledge, attitudes and practices of community health workers in maternal and infant health: a randomized controlled study.BMC medical education · 2018Trial
- A district-based health facility assessment for maternal and newborn care across Pakistan.Journal of global health · 2026Article
- Mortality impact of implementing maternal perinatal deaths surveillance and response quality-of-care improvement strategy for maternal and newborn care, northeast Namibia: a quasi-experimental study.Journal of global health · 2026Article
- Pathways of change for essential newborn care practices and health care seeking: a process evaluation of Mamás del Río, a community-based, maternal and neonatal health intervention in the Peruvian Amazon.Health policy and planning · 2026Article
- Universal Transcutaneous Bilirubin Screening in a Midwifery-Led Home Care Setting.JAMA network open · 2026Article
- Integrating Indigenous Maya practices and digital health tools to improve outcomes for Indigenous newborns in Guatemala: a community-based initiative.Global health action · 2025Article
- Impact of home-visit counselling on maternal and child health and nutrition by Barangay health workers: a quasi-experimental study from Eastern Visayas, Philippines.Journal of global health · 2025Article
- Midwives' willingness to provide home-based maternity and child health care, along with the associated factors and barriers, in Gondar, Ethiopia.Frontiers in global women's health · 2025Article
- Article
- Community-based postnatal care model: Catalyst for management of mothers and neonates.Curationis · 2024Article
- Postnatal quality of care measures for mothers and newborns at home: A scoping review.PLOS global public health · 2024Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The objective of this review is to assess the effect of home-based neonatal care provided by community health workers (CHWs) for preventing neonatal, infant and perinatal mortality in resource-limited settings with poor access to health facility-based care. The authors conducted a systematic review, including meta-analysis and meta-regression of controlled trials. The data sources included electronic databases, with a hand search of reviews, abstracts and proceedings of conferences to search for randomized, or cluster randomized, controlled trials evaluating the effect of home-based neonatal care provided by CHWs for preventing neonatal, infant and perinatal mortality. Among the included trials, all from South Asian countries, information on neonatal, infant and perinatal mortality was available in five, one and three trials, respectively. The intervention package comprised three components, namely, home visits during pregnancy (four trials), home-based preventive and/or curative neonatal care (all trials) and community mobilization efforts (four trials). Intervention was associated with a reduced risk of mortality during the neonatal (random effects model relative risk (RR) 0.75; 95% confidence intervals (CIs) 0.61 to 0.92, P=0.005; I(2)=82.2%, P<0.001 for heterogeneity; high-quality evidence) and perinatal periods (random effects model RR 0.78; 95% CI 0.64 to 0.94, P=0.009; I(2)=79.6%, P=0.007 for heterogeneity; high-quality evidence). In one trial, a significant decline in infant mortality (RR 0.85; 95% CI 0.77 to 0.94) was documented. Subgroup and meta-regression analyses suggested a greater effect with a higher baseline neonatal mortality rate. The authors concluded that home-based neonatal care is associated with a reduction in neonatal and perinatal mortality in South Asian settings with high neonatal-mortality rates and poor access to health facility-based care. Adoption of a policy of home-based neonatal care provided by CHWs is justified in such settings.
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