SynthesisJournal of perinatology : official journal of the California Perinatal Association2016
When do newborns die? A systematic review of timing of overall and cause-specific neonatal deaths in developing countries.
Synthesis in Journal of perinatology : official journal of the California Perinatal Association, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 126 papers, 4 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
126 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Exploring parental knowledge, care-seeking, and support strategies for neonatal illness: an integrative review of the African Great Lakes region.Global health action · 2025Pooled it
- Kangaroo mother care for preterm or low birth weight infants: a systematic review and meta-analysis.BMJ global health · 2023Pooled it
- Timing of maternal mortality and severe morbidity during the postpartum period: a systematic review.JBI evidence synthesis · 2022Pooled it
- Congenital heart disease diagnosed with echocardiogram in newborns with asymptomatic cardiac murmurs: a systematic review.BMC pediatrics · 2020Pooled it
- Etiology of severe invasive infections in young infants in rural settings in sub-Saharan Africa.PloS one · 2022Trial
- Effectiveness of self-managed continuous monitoring for maintaining high-quality early essential newborn care compared to supervision visit in Lao PDR: a cluster randomised controlled trial.BMC health services research · 2021Trial
- Risk factors and mortality in infants who received bag and mask ventilation at birth: a secondary analysis from the global network maternal newborn health registry.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Development of a prediction model for infant hospitalisation and death using clinical features assessed by community health workers during routine postnatal home visits in Dhaka, Bangladesh.BMJ paediatrics open · 2026Article
- Digestive congenital anomalies: a call for equity in global neonatal surgical care.Pediatric research · 2026Article
- Spatiotemporal variation and decomposition of early neonatal mortality in Ethiopia using demographic health survey data.Scientific reports · 2026Article
- Health system readiness for immediate Kangaroo Mother Care (iKMC) among network of care facilities in the Sidama region, Ethiopia: a mixed-method study.Gates open research · 2026Article
- Integrating immediate Kangaroo Mother Care as an integral part of small and sick newborn care in facilities with level 2 Special Newborn Care Units: Implementation Research Protocol.Gates open research · 2026Article
- Ambient temperature extremes and neonatal mortality: a time-stratified case-crossover analysis using Demographic and Health Survey data from East Africa (2011-2022).BMJ public health · 2026Article
- Article
- Survival and Causes of Death in Infants Admitted in NICU in Iran: A Retrospective Cohort Study 2016-2022.Iranian journal of public health · 2025Article
- Risk factors of under-five mortality in Tanzania: insights from the Tanzania Demographic and Health Survey 2022.BMJ global health · 2025Article
- Maternal awareness of newborn danger signs before discharge: a secondary analysis of baseline data from a quasi-experimental study in Uganda.Maternal health, neonatology and perinatology · 2025Article
- Antenatal corticosteroids for pregnant women at risk of preterm labour in low- and middle-income countries: utilisation and facility readiness.Journal of global health · 2025Article
- Time series analysis for forecasting neonatal intensive care unit census and neonatal mortality.BMC pediatrics · 2025Article
- Comparison of risk factors, clinical characteristics, laboratory findings and bacterial etiology between early-onset and late-onset neonatal sepsis in Sana'a City, Yemen.BMC pediatrics · 2025Article
66 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
About 99% of neonatal deaths occur in low- and middle-income countries. There is a paucity of information on the exact timing of neonatal deaths in these settings. The objective of this review was to determine the timing of overall and cause-specific neonatal deaths in developing country settings. We searched MEDLINE via PubMed, Cochrane CENTRAL, WHOLIS and CABI using sensitive search strategies. Searches were limited to studies involving humans published in the last 10 years. A total of 22 studies were included in the review. Pooled results indicate that about 62% of the total neonatal deaths occurred during the first 3 days of life; the first day alone accounted for two-thirds. Almost all asphyxia-related and the majority of prematurity- and malformation-related deaths occurred in the first week of life (98%, 83% and 78%, respectively). Only one-half of sepsis-related deaths occurred in the first week while one-quarter occurred in each of the second and third to fourth weeks of life. The distribution of both overall and cause-specific mortality did not differ greatly between Asia and Africa. The first 3 days after birth account for about 30% of under-five child deaths. The first week of life accounts for most of asphyxia-, prematurity- and malformation-related mortality and one-half of sepsis-related deaths.
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