Evidence map›Paper›PMID 27108848›Full record

ArticleInfection control and hospital epidemiology2016

Research Methods in Healthcare Epidemiology and Antimicrobial Stewardship: Randomized Controlled Trials.

Deverick J Anderson, Manisha Juthani-Mehta, Daniel J Morgan

Abstract read
In one paragraph

Article in Infection control and hospital epidemiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Deverick J Anderson1Duke University Medical Center,Division of Infectious Diseases,Durham,North Carolina.
Manisha Juthani-Mehta2Yale University School of Medicine,Department of Internal Medicine,Section of Infectious Diseases,New Haven,Connecticut.
Daniel J Morgan3VA Maryland Healthcare System and University of Maryland School of Medicine,Baltimore,Maryland.

Funding

Clinical and Molecular Epidemiology of Multidrug-Resistant Organisms in a CommuniK23AI095357 · NIAID · DUKE UNIVERSITY · PI ANDERSON, DEVERICK JOHN · 2011 to 2015
$644k
NIAID NIH HHS K23 AI095357
6 · The paper itself

Abstract

Randomized controlled trials (RCT) produce the strongest level of clinical evidence when comparing interventions. RCTs are technically difficult, costly, and require specific considerations including the use of patient- and cluster-level randomization and outcome selection. In this methods paper, we focus on key considerations for RCT methods in healthcare epidemiology and antimicrobial stewardship (HE&AS) research, including the need for cluster randomization, conduct at multiple sites, behavior modification interventions, and difficulty with identifying appropriate outcomes. We review key RCTs in HE&AS with a focus on advantages and disadvantages of methods used. A checklist is provided to aid in the development of RCTs in HE&AS. Infect Control Hosp Epidemiol 2016;37:629-634.

Indexed as

Antimicrobial StewardshipHealth Services ResearchHumansRandomized Controlled Trials as Topic

Identifiers

PMID27108848
PMCPMC8662919

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.