SynthesisEuropean radiology2017
Complication rates of CT-guided transthoracic lung biopsy: meta-analysis.
Synthesis in European radiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 370 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Post-Procedural Rapid Rollover on Pneumothorax After Percutaneous CT-Guided Lung Biopsy: A Randomized Controlled Trial
Evaluation of the the Effectiveness of the Autologous Blood Patch Method in Transthoracic Lung Biopsies Using the Coaxial Technique
Complications After CT-guided Lung Biopsies at St. Olavs Hospital
Comparative Study of Rotational Cryobiopsy Needle and Automated Biopsy Needle in Transthoracic Needle Biopsy for the Diagnosis of Peripheral Pulmonary Lesions
Who cites it
370 citing papers in PubMed, 6 syntheses or guidelines pooled it, 724 citations in OpenAlex.
- Robotic-assisted transbronchial biopsy versus computed tomography-guided transthoracic needle biopsy for peripheral pulmonary lesions: a systematic review and meta-analysis of direct comparative studies.Journal of robotic surgery · 2026Pooled it
- Diagnostic yield and safety of diagnostic techniques for pulmonary lesions: systematic review, meta-analysis and network meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2024Pooled it
- A systematic review and meta-analysis of randomized controlled trials comparing low-dose versus standard-dose computed tomography-guided lung biopsy.Journal of cardiothoracic surgery · 2024Pooled it
- Autologous blood patch intraparenchymal injection reduces the incidence of pneumothorax and the need for chest tube placement following CT-guided lung biopsy: a systematic review and meta-analysis.European journal of medical research · 2024Pooled it
- Risk factors for air embolism following computed tomography-guided percutaneous transthoracic needle biopsy: a systematic review and meta-analysisDiagnostic and interventional radiology (Ankara, Turkey) · 2023Pooled it
- Pooled it
- Three-dimensionally printed navigational template technology for lung biopsy: a noninferiority, randomized trial.International journal of surgery (London, England) · 2026Trial
- Trial
- Extracellular Vesicle Protein Panel Enables Early Lung Cancer Detection in a Large Clinical Cohort.Journal of extracellular vesicles · 2025Trial
- [Application of Rapid HE Staining in Cytological Rapid On-site Evaluation of Peripheral Lung Cancer Needle Biopsy].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2023Trial
- Comparative study of transbronchial cryobiopsy and transbronchial biopsy for diagnostic yield in peripheral pulmonary lesions.Annals of medicine · 2026Article
- Trans-osseous coaxial biopsy for pulmonary lesions under CT guidance: Technical efficacy for challenging location.European journal of radiology open · 2026Article
- Association between intraprocedural oxygen administration and postprocedural pneumothorax after ct-guided transthoracic lung biopsy.BMC pulmonary medicine · 2026Article
- Procedural efficiency, diagnostic yield, and safety of a novel positioning grid combined with a non-coplanar puncture-angle guide for CT-guided percutaneous transthoracic lung biopsy: a retrospective contemporaneous-control study.Journal of thoracic disease · 2026Article
- Diagnostic yield and predictors of complications in CT-guided percutaneous lung biopsy: an analysis based on ATS/ACCP criteria.La Radiologia medica · 2026Article
- The RATAB Framework: An Interpretable AI-Driven Radiographic Risk Stratification Model for Suspected Lung Lesions.Journal of imaging informatics in medicine · 2026Article
- Efficacy and safety of the RC120 navigation system for the computed tomography-guided localization of pulmonary ground-glass nodules: a prospective study with historical controls.Quantitative imaging in medicine and surgery · 2026Article
- Tool-in-lesion confirmation and diagnostic yield of digital tomosynthesis-integrated robotic bronchoscopic biopsy of lung nodules.Translational lung cancer research · 2026Article
- Diagnostic Outcomes of Robotic Bronchoscopy in a Multidisciplinary, Multi-hospital Lung Nodule Program.The Journal of surgical research · 2026Observational
- Use of the Ion Robot in the Diagnosis of Pulmonary Nodules: Fine Needle Aspiration Versus Cryobiopsy.Diagnostic cytopathology · 2026Article
310 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo meta-analyze complication rate in computed tomography (CT)-guided transthoracic lung biopsy and associated risk factors.
methodsFour databases were searched from 1/2000 to 8/2015 for studies reporting complications in CT-guided lung biopsy. Overall and major complication rates were pooled and compared between core biopsy and fine needle aspiration (FNA) using the random-effects model. Risk factors for complications in core biopsy and FNA were identified in meta-regression analysis.
resultsFor core biopsy, 32 articles (8,133 procedures) were included and for FNA, 17 (4,620 procedures). Pooled overall complication rates for core biopsy and FNA were 38.8 % (95 % CI: 34.3-43.5 %) and 24.0 % (95 % CI: 18.2-30.8 %), respectively. Major complication rates were 5.7 % (95 % CI: 4.4-7.4 %) and 4.4 % (95 % CI: 2.7-7.0 %), respectively. Overall complication rate was higher for core biopsy compared to FNA (p < 0.001). For FNA, larger needle diameter was a risk factor for overall complications, and increased traversed lung parenchyma and smaller lesion size were risk factors for major complications. For core biopsy, no significant risk factors were identified.
conclusionsIn CT-guided lung biopsy, minor complications were common and occurred more often in core biopsy than FNA. Major complication rate was low. For FNA, smaller nodule diameter, larger needle diameter and increased traversed lung parenchyma were risk factors for complications. KEY POINTS: • Minor complications are common in CT-guided lung biopsy • Major complication rate is low in CT-guided lung biopsy • CT-guided lung biopsy complications occur more often in core biopsy than FNA • Major complication rate is similar in core biopsy and FNA • Risk factors for FNA are larger needle diameter, smaller lesion size.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.