ArticleClinical research in cardiology : official journal of the German Cardiac Society2016
Temporal deformation pattern in acute and late phases of ST-elevation myocardial infarction: incremental value of longitudinal post-systolic strain to assess myocardial viability.
Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01109225 (Multiparametric Study of Cardiac Remodeling After Myocardial Infarction Revascularized in Acute Phase), which is not on this map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Multiparametric Study of Cardiac Remodeling After Myocardial Infarction Revascularized in Acute Phase : Relation With the Serum Concentrations in Aldosterone
Who cites it
16 citing papers in PubMed.
- Effect of eplerenone on extracellular cardiac matrix biomarkers in patients with acute ST-elevation myocardial infarction without heart failure: insights from the randomized double-blind REMINDER Study.Clinical research in cardiology : official journal of the German Cardiac Society · 2018Trial
- Intra-procedural determination of viability by myocardial deformation imaging: a randomized prospective study in the cardiac catheter laboratory.Clinical research in cardiology : official journal of the German Cardiac Society · 2017Trial
- Potential predictive value of myocardial strain and strain rate for late gadolinium enhancement in children with a history of Kawasaki disease.Quantitative imaging in medicine and surgery · 2025Article
- Global, segmental, and layer-specific two-dimensional speckle tracking echocardiography immediately after acute myocardial infarction as a predictive tool to assess myocardial viability and scar size.Journal of echocardiography · 2025Article
- Parameter subset reduction for imaging-based digital twin generation of patients with left ventricular mechanical discoordination.Biomedical engineering online · 2024Article
- Diagnostic potential of myocardial early systolic lengthening for patients with suspected non-ST-segment elevation acute coronary syndrome.BMC cardiovascular disorders · 2023Article
- Myocardial deformation in malignant mitral valve prolapse: A shifting paradigm to dynamic mitral valve-ventricular interactions.Frontiers in cardiovascular medicine · 2023Article
- Impact of apical and mid-ventricular transmural infarcts in patients with acute myocardial infarction determined by using late gadolinium enhancement combined with feature tracking magnetic resonance.Cardiovascular diagnosis and therapy · 2022Article
- A Lumped Two-Compartment Model for Simulation of Ventricular Pump and Tissue Mechanics in Ischemic Heart Disease.Frontiers in physiology · 2022Article
- Comprehensive Assessment of the Left Ventricular Systolic Function in the Elderly with Acute Myocardial Infarction Using Echocardiography.International journal of general medicine · 2022Article
- Myocardial Postsystolic Shortening and Early Systolic Lengthening: Current Status and Future Directions.Diagnostics (Basel, Switzerland) · 2021Review
- Echocardiography and cardiovascular magnetic resonance based evaluation of myocardial strain and relationship with late gadolinium enhancement.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2019Article
- Test-retest reliability of new and conventional echocardiographic parameters of left ventricular systolic function.Clinical research in cardiology : official journal of the German Cardiac Society · 2019Article
- Value of the CHAClinical research in cardiology : official journal of the German Cardiac Society · 2018Article
- Aborted sudden cardiac death: ICD or no ICD.Clinical research in cardiology : official journal of the German Cardiac Society · 2017Article
- NT-proBNP and Echocardiographic Parameters for Prediction of Cardiovascular Outcomes in Patients with CKD Stages G2-G4.Clinical journal of the American Society of Nephrology : CJASN · 2016Article
Corrections and comments
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Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIdentification of transmural extent and degree of non-viability after ST-segment elevation myocardial infarction (STEMI) is clinically important. The objective of the present study was to assess the regional mechanics and temporal deformation patterns using speckle tracking echocardiography (STE) in acute and later phases of STEMI to predict myocardial damage in these patients. METHODS AND
resultsNinety-eight patients with first STEMI underwent both echocardiography and cardiac magnetic resonance imaging in acute phase and at 6 months follow-up with 2D STE-derived measurements of peak longitudinal strain (PLS), Pre-STretch index (PST) and post-systolic deformation index (PSI). For each segment, late gadolinium enhancement (LGE) was defined as transmural (LGE >66 %) or non-transmural (<66 %). Global deformation values were significantly correlated with LVEFCMR and infarct size at both visits. A significantly lower value of segmental PLS and higher PSI and PST in necrotic segments were observed comparatively to control, adjacent and remote segments. The best parameters to predict transmural extent in acute phase were PSI with a cutoff value of 8 % (AUC: 0.84) and PLS with a cutoff value of -13 % (AUC: 0.86). PST showed high specificity, but poor sensitivity in predicting transmural extent. More importantly, the addition of PSI and PST to PLS in acute phase was associated with improved prediction of viability at 6 months (integrated discrimination improvement 2.5 % p < 0.01; net reclassification improvement 27 %; p < 0.01).
conclusionsAll systolic deformation values separated transmural from non-transmural scarring. PLS combined with additional information relative to post-systolic deformation appears to be the most informative parameters to predict the transmural extent of MI in the early and late phases of MI. CLINICAL
trial registrationhttp://clinicaltrials.gov/show/NCT01109225 ; NCT01109225.
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