Evidence map›Paper›PMID 27108063›Full record

ReviewBiochimica et biophysica acta2016

Recent discoveries on absorption of dietary fat: Presence, synthesis, and metabolism of cytoplasmic lipid droplets within enterocytes.

Theresa D'Aquila, Yu-Han Hung, Alicia Carreiro, Kimberly K Buhman

Open access · greenAbstract readReview
In one paragraph

Review in Biochimica et biophysica acta, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed
10.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 129 citations in OpenAlex.

  1. Trial
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  3. Oral Glucose Mobilizes Triglyceride Stores From the Human Intestine.Cellular and molecular gastroenterology and hepatology · 2019
    Trial
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8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Theresa D'AquilaDepartment of Nutrition Science, Purdue University, West Lafayette, IN 47907, USA.
Yu-Han HungDepartment of Nutrition Science, Purdue University, West Lafayette, IN 47907, USA.
Alicia CarreiroDepartment of Nutrition Science, Purdue University, West Lafayette, IN 47907, USA.
Kimberly K BuhmanDepartment of Nutrition Science, Purdue University, West Lafayette, IN 47907, USA. Electronic address: kbuhman@purdue.edu.
Purdue University West Lafayette · US

Funding

Indiana Clinical and Translational Sciences InstituteUL1TR001108 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI DENNE, SCOTT C., SHEKHAR, ANANTHA · 2013 to 2017
$23.3M
Interdisciplinary Training in Signals Controlling Ingestion and ObesityT32DK076540 · NIDDK · PURDUE UNIVERSITY · PI MATTES, RICHARD D · 2008 to 2018
$766k
NCATS NIH HHS UL1 TR001108NCATS NIH HHS UL1TR001108NIDDK NIH HHS 5T32DK076540-07NIDDK NIH HHS T32 DK076540
6 · The paper itself

Abstract

Dietary fat provides essential nutrients, contributes to energy balance, and regulates blood lipid concentrations. These functions are important to health, but can also become dysregulated and contribute to diseases such as obesity, diabetes, cardiovascular disease, and cancer. Within enterocytes, the digestive products of dietary fat are re-synthesized into triacylglycerol, which is either secreted on chylomicrons or stored within cytoplasmic lipid droplets (CLDs). CLDs were originally thought to be inert stores of neutral lipids, but are now recognized as dynamic organelles that function in multiple cellular processes in addition to lipid metabolism. This review will highlight recent discoveries related to dietary fat absorption with an emphasis on the presence, synthesis, and metabolism of CLDs within this process.

Indexed as

Lipid MetabolismAdsorptionAnimalsCardiovascular DiseasesChylomicronsCytoplasmDiabetes MellitusDietary FatsEnterocytesHumansLipid DropletsNeoplasmsObesityChylomicronsDietary FatsChylomicronCytoplasmic lipid dropletDietary fat absorptionEnterocyteLipid metabolismSmall intestineTriacylglycerol

Identifiers

PMID27108063
PMCPMC5503208
OpenAlexW2337088385

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.