Evidence map›Paper›PMID 27107856›Full record

ArticleVirus genes2016

Molecular evolution of epizootic hemorrhagic disease viruses in North America based on historical isolates using motif fingerprints.

W C Wilson, M G Ruder, D Jasperson, T P L Smith, P Naraghi-Arani, R Lenhoff, D E Stallknecht, W A Valdivia-Granda, D Sheoran

Abstract read
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In one paragraph

Article in Virus genes, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
5.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Clustering ofFrontiers in public health · 2019
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

W C WilsonArthropod-Borne Animal Diseases Research Unit, Center for Grain and Animal Health Research, United States Department of Agriculture, Agricultural Research Service, 1515 College Ave., Manhattan, KS, 66502, USA. william.wilson@ars.usda.gov.
M G RuderArthropod-Borne Animal Diseases Research Unit, Center for Grain and Animal Health Research, United States Department of Agriculture, Agricultural Research Service, 1515 College Ave., Manhattan, KS, 66502, USA.
D JaspersonArthropod-Borne Animal Diseases Research Unit, Center for Grain and Animal Health Research, United States Department of Agriculture, Agricultural Research Service, 1515 College Ave., Manhattan, KS, 66502, USA.
T P L SmithU.S. Meat Animal Research Center, United States Department of Agriculture, Agricultural Research Service, Clay Center, NE, USA.
P Naraghi-AraniAssay Development and Virology, Lawrence Livermore National Laboratories, Livermore, CA, USA.
R LenhoffAssay Development and Virology, Lawrence Livermore National Laboratories, Livermore, CA, USA.
D E StallknechtSoutheastern Cooperative Wildlife Disease Study, Department of Population Health, College of Veterinary Medicine, University of Georgia, Athens, GA, USA.
W A Valdivia-GrandaOrion Integrated Biosciences Inc., New Rochelle, NY, USA.
D SheoranOrion Integrated Biosciences Inc., New Rochelle, NY, USA.
Lawrence Livermore National Laboratory · USUnited States Department of Agriculture · USAgricultural Research Service · USCenter for Grain and Animal Health Research · USUniversity of Georgia · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epizootic hemorrhagic disease virus (EHDV) is an orbivirus of the Reoviridae family that has significant impact on wild and captive white-tailed deer. Although closely related to bluetongue virus that can cause disease in sheep and cattle, North American EHDV historically has not been associated with disease in cattle or sheep. Severe disease in cattle has been reported with other EHDV strains from East Asia and the Middle East. To understand the potential role of viral genetics in the epidemiology of epizootic hemorrhagic disease, a molecular characterization of North American EHDV strains from 1955 to 2012 was conducted via conventional phylogenetic analysis and a new classification approach using motif fingerprint patterns. Overall, this study indicates that the genetic make-up of EHDV populations in North America have slowly evolved over time. The data also suggested limited reassortment events between serotypes 1 and 2 and introduces a new analysis tool for more detailed sequence pattern analysis.

Indexed as

AnimalsCattleEvolution, MolecularHemorrhagic Disease Virus, EpizooticInsectaNorth AmericaPhylogenyReoviridae InfectionsEpizootic hemorrhagic diseaseMolecular evolutionMotif fingerprint

Identifiers

PMID27107856
OpenAlexW2339291678

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.