Trial reportPsychiatry research. Neuroimaging2016
Neurophysiological mechanisms in acceptance and commitment therapy in opioid-addicted patients with chronic pain.
Trial report in Psychiatry research. Neuroimaging, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effects of Chronic Pain Treatment on Altered Functional and Metabolic Activities in the Brain: A Systematic Review and Meta-Analysis of Functional Neuroimaging Studies.Frontiers in neuroscience · 2021Pooled it
- An evaluation of the feasibility, acceptability, and preliminary efficacy of cognitive-behavioral therapy for opioid use disorder and chronic pain.Drug and alcohol dependence · 2019Trial
- Pharmacological and behavioral pain treatment strategies for patients with opioid use disorder.Expert opinion on pharmacotherapy · 2025Review
- Persisting with Purpose: Using Acceptance and Commitment Therapy to Target Comorbid Opioid Use Disorder and Chronic Pain in a Racially and Economically Marginalized Population.Journal of contextual behavioral science · 2025Article
- Neural correlates of pain acceptance and the role of the cerebellum: Functional connectivity and anatomical differences in individuals with headaches versus matched controls.European journal of pain (London, England) · 2025Article
- Potential Mechanisms of Action and Outcomes of Equine-Assisted Services for Veterans with a History of Trauma: A Narrative Review of the Literature.International journal of environmental research and public health · 2023Review
- Effects of acceptance and commitment therapy on cognitive function: A systematic review.Heliyon · 2023Review
- Classification of Mindfulness Meditation and Its Impact on Neural Measures in the Clinical Population.Frontiers in psychology · 2022Review
- The missing mechanistic link: Improving behavioral treatment efficacy for pediatric chronic pain.Frontiers in pain research (Lausanne, Switzerland) · 2022Review
- Acceptance and Commitment Therapy in a Low-Income Country in Sub-Saharan Africa: A Call for Further Research.Frontiers in public health · 2021Article
- Neural Mechanisms of Acceptance and Commitment Therapy for Chronic Pain: A Network-Based fMRI Approach.Frontiers in human neuroscience · 2021Article
- Adapting behavioural interventions to compensate for cognitive dysfunction in persons with opioid use disorder.General psychiatry · 2021Review
- Biological mechanism study of meditation and its application in mental disorders.General psychiatry · 2020Review
- Building a Group-Based Opioid Treatment (GBOT) blueprint: a qualitative study delineating GBOT implementation.Addiction science & clinical practice · 2019Article
- Bringing Neuroscience to the Bedside.Focus (American Psychiatric Publishing) · 2019Article
- Network Alterations in Comorbid Chronic Pain and Opioid Addiction: An Exploratory Approach.Frontiers in human neuroscience · 2019Article
- Mindfulness-Based Interventions for the Treatment of Substance and Behavioral Addictions: A Systematic Review.Frontiers in psychiatry · 2018Article
- Current status of acceptance and commitment therapy for chronic pain: a narrative review.Journal of pain research · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Acceptance and Commitment Therapy (ACT) has been effectively utilized to treat both chronic pain and substance use disorder independently. Given these results and the vital need to treat the comorbidity of the two disorders, a pilot ACT treatment was implemented in individuals with comorbid chronic pain and opioid addiction. This pilot study supported using neurophysiology to characterize treatment effects and revealed that, following ACT, participants with this comorbidity exhibited reductions in brain activation due to painful stimulus and in connectivity at rest.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.