Evidence map›Paper›PMID 27106901›Full record

Trial reportAging clinical and experimental research2017

My Mind Project: the effects of cognitive training for elderly-the study protocol of a prospective randomized intervention study.

C Giuli, P Fattoretti, C Gagliardi, E Mocchegiani, D Venarucci, M Balietti, T Casoli, L Costarelli, R Giacconi, M Malavolta and 3 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Aging clinical and experimental research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

C GiuliGeriatrics Operative Unit, Italian National Research Centre on Aging (INRCA) IRCCS, Contrada Mossa, 63900, Fermo, Italy. c.giuli@inrca.it.
P FattorettiCenter for Neurobiology of Aging, Italian National Research Centre on Aging (INRCA), via Birarelli, Ancona, Italy.
C GagliardiCentre of Socio-Economic Gerontological Research, Italian National Research Centre on Aging (INRCA), via S. Margherita, Ancona, Italy.
E MocchegianiNutrition and Aging Centre, Italian National Research Centre on Aging (INRCA), via Birarelli, Ancona, Italy.
D VenarucciBiochemical Operative Unit, Italian National Research Centre on Aging (INRCA), Contrada Mossa, Fermo, Italy.
M BaliettiCenter for Neurobiology of Aging, Italian National Research Centre on Aging (INRCA), via Birarelli, Ancona, Italy.
T CasoliCenter for Neurobiology of Aging, Italian National Research Centre on Aging (INRCA), via Birarelli, Ancona, Italy.
L CostarelliNutrition and Aging Centre, Italian National Research Centre on Aging (INRCA), via Birarelli, Ancona, Italy.
R GiacconiNutrition and Aging Centre, Italian National Research Centre on Aging (INRCA), via Birarelli, Ancona, Italy.
M MalavoltaNutrition and Aging Centre, Italian National Research Centre on Aging (INRCA), via Birarelli, Ancona, Italy.
R PapaCentre of Socio-Economic Gerontological Research, Italian National Research Centre on Aging (INRCA), via S. Margherita, Ancona, Italy.
F LattanzioScientific Direction, Italian National Research Centre on Aging (INRCA), via S. Margherita, Ancona, Italy.
D PostacchiniGeriatrics Operative Unit, Italian National Research Centre on Aging (INRCA) IRCCS, Contrada Mossa, 63900, Fermo, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCognitive decline and dementia represent a key problem for public health as they heavily impair social functioning and independent living. The development of new strategies to support recommendations for patients and their caregivers may represent an outstanding step forward.

aimsTo describe the study protocol and methods of "My Mind Project: the effect of cognitive training for elderly" (Grant No. 154/GR-2009-1584108), which investigates, by the use of a multidisciplinary approach, the effects of a comprehensive cognitive training programme on performances in aged subjects with mild-moderate Alzheimer's disease, mild cognitive impairment and normal cognitive functioning.

methodsThe study is a prospective randomized intervention for the assessment of cognitive training effects in three groups of elderly subjects with different cognitive status. A total of 321 elderly people were enrolled in Marche Region, Italy. Each subject was randomly assigned to an experimental group or to a control group. Cognitive performances and biochemical blood markers have also been analysed before cognitive training (baseline), immediately after termination (follow-up 1), after 6 months (follow-up 2) and after 2 years (follow-up 3). DISCUSSION: The results will be useful to identify some efficient programmes for the enhancement of cognitive performance in elderly with and without cognitive decline.

conclusionThe application of a non-pharmacological approach in the treatment of elderly with cognitive disorders could have a profound impact on National Health Service.

Indexed as

AgedAlzheimer DiseaseClinical ProtocolsCognitive DysfunctionHumansItalyMemoryProspective StudiesAlzheimer’s diseaseBiomarkersCognitive trainingElderly peopleMild cognitive impairment

Identifiers

PMID27106901
PMCPMC5445186

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.