ArticleEndocrine2016
Prevalence and determinants of vitamin D deficiency in healthy French adults: the VARIETE study.
Article in Endocrine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03232216 (Vitamin D Supplementation in Patients With Operated Tibia Fracture and Low Vitamin D. Does it Improve Healing Rate?. Randomized Controlled Trial), which is not on this map. Cited by 33 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Vitamin D Supplementation in Patients With Operated Tibia Fracture and Low Vitamin D. Does it Improve Healing Rate?. Randomized Controlled Trial
Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 74 citations in OpenAlex.
- High prevalence of vitamin D deficiency among the South Asian adults: a systematic review and meta-analysis.BMC public health · 2021Pooled it
- Pharmacokinetics of a New Pharmaceutical Form of Vitamin D3 100,000 IU in Soft Capsule.Nutrients · 2019Trial
- Vitamin D status of adults in the North of the Netherlands: cross-sectional results from the Lifelines cohort study.European journal of clinical nutrition · 2025Article
- Vitamin D deficiency in Ukraine: A multicentre cross-sectional study.Global epidemiology · 2024Article
- Bone mineral density in adults with arthrogryposis multiplex congenita: a retrospective cohort analysis.Scientific reports · 2024Article
- Vitamin D Status in the Adult Population of Romania-Results of the European Health Examination Survey.Nutrients · 2024Article
- Retrospective Analysis of Vitamin D Deficiency in an Adult Population of Arad County, Western Romania (2019-2022).Life (Basel, Switzerland) · 2024Article
- Prevalence and Causes of Vitamin D Deficiency in a Cohort of Greek HIV-Infected Individuals: A Prospective, Single Center, Observational Study.Current HIV research · 2024Observational
- Association of Vitamin D Deficiency and Insufficiency with Pathology in Hospitalized Patients.Diagnostics (Basel, Switzerland) · 2023Article
- COVID-19 infection and metabolic comorbidities: Mitigating role of nutritional sufficiency and drug - nutraceutical combinations of vitamin D.Human nutrition & metabolism · 2023Review
- Vitamin D Supply of Multivitamins Commercialized Online by Amazon in Western and Southern Europe: A Labeling Analysis.Nutrients · 2023Article
- Using FIGO Nutrition Checklist counselling in pregnancy: A review to support healthcare professionals.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2023Review
- Article
- No Association between Vitamin D and Weight Gain: A Prospective, Population-Based Study.Nutrients · 2022Article
- Vitamin D in healthy Tunisian population: Preliminary results.Journal of medical biochemistry · 2022Article
- A Systematic Review of Vitamin D Status and Dietary Intake in Various Slovenian Populations.Zdravstveno varstvo · 2022Article
- A critical update on the role of mild and serious vitamin D deficiency prevalence and the COVID-19 epidemic in Europe.Nutrition (Burbank, Los Angeles County, Calif.) · 2022Article
- Blood microbiota and metabolomic signature of major depression before and after antidepressant treatment: a prospective case-control study.Journal of psychiatry & neuroscience : JPN · 2021Article
- Baseline Levels of Vitamin D in a Healthy Population from a Region with High Solar Irradiation.Nutrients · 2021Article
- The role of vitamin D in perinatology. An up-to-date review.Archives of medical science : AMS · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The U.S. Institute of Medicine considers that a serum 25-hydroxyvitamin D (25OHD) concentration >20 ng/mL corresponds to optimal vitamin D status in the general population. Old studies of vitamin D status in the French general population have demonstrated high prevalence of insufficiency. We measured serum 25OHD, 1,25(OH)2D, PTH, calcium, phosphorus, and creatinine levels in 892 French Caucasian healthy subjects (463 men, 429 women) aged from 18 to 89 years. The 25OHD concentration was similar in men (24.1 ± 8.2 ng/mL) and women (23.4 ± 8.0 ng/mL). 25OHD concentrations of <10, <12, <20, and <30 ng/mL were found in respectively 6.3, 9.9, 34.6, and 80.3 % of subjects. Residence in northern France (odds ratio [OR] 1.91), blood sampling between January and March (OR 7.74), BMI ≥24 kg/m(2) (OR 1.81), and age 60 years or more (OR 1.99) were significant determinants of hypovitaminosis D (25OHD <20 ng/mL). The serum 25OHD level correlated positively with 1,25(OH)2D and negatively with PTH. 25OHD values below 20 ng/mL were associated with lower 1,25(OH)2D levels, and 25OHD values below 27 ng/mL were associated with higher PTH levels. Many French healthy adults have a 25OHD concentration <20 ng/mL, especially during winter months. Actions to improve the vitamin D status of the French general population are urgently needed.
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Registered trials
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