Observational studyJournal of neurointerventional surgery2017
Proteinuria as an independent risk factor for contrast-induced acute kidney injury and mortality in patients with stroke undergoing cerebral angiography.
Observational study in Journal of neurointerventional surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Incidence, risk factors, and outcomes of contrast-associated acute kidney injury following interventional radiology procedures: a systematic review and meta-analysis.Frontiers in radiology · 2026Pooled it
- Preoperative proteinuria may be a risk factor for postoperative acute kidney injury：a meta-analysis.Renal failure · 2021Pooled it
- In-hospital electronic monitoring system approaches to epidemiologic investigation and predictive modeling of contrast-induced acute kidney injury.Renal failure · 2026Article
- An online dynamic nomogram for predicting acute kidney injury after endovascular therapy in acute ischemic stroke.BMC nephrology · 2026Article
- Stroke-Induced Renal Dysfunction: Underlying Mechanisms and Challenges of the Brain-Kidney Axis.CNS neuroscience & therapeutics · 2024Review
- Biomarkers in Contrast-Induced Acute Kidney Injury: Towards A New Perspective.International journal of molecular sciences · 2024Review
- Article
- External Validation of the Nelson Equation for Kidney Function Decline in Patients with Acute Ischemic Stroke or Transient Ischemic Attack.Clinical interventions in aging · 2023Article
- Contrast-Induced Acute Kidney Injury in Radiologic Management of Acute Ischemic Stroke in the Emergency Setting.AJNR. American journal of neuroradiology · 2020Observational
- Brain-kidney interaction: Renal dysfunction following ischemic stroke.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2020Review
- Cerebral ischemia induces TRPC6 via HIF1α/ZEB2 axis in the glomerular podocytes and contributes to proteinuria.Scientific reports · 2019Article
- Safety of cerebral angiography and neuroendovascular therapy in patients with chronic kidney disease.Neuroradiology · 2018Article
- Acute kidney injury and stroke: unresolved issues.Internal and emergency medicine · 2018Article
- Predictors and Outcomes of Postcontrast Acute Kidney Injury after Endovascular Renal Artery Intervention.Journal of vascular and interventional radiology : JVIR · 2017Article
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe correlation between proteinuria and contrast-induced acute kidney injury (CI-AKI) in patients with cerebrovascular disease is still unknown.
objectiveTo determine whether proteinuria is a risk factor for CI-AKI and death in patients with stroke undergoing cerebral angiography.
methodsData from 2015 patients with stroke undergoing cerebral angiography between January 2009 and December 2013 were retrospectively collected. Clinical parameters were obtained from the hospital's computerized database. All variables were analyzed by univariate analysis and multivariate logistic regression analysis.
resultsCI-AKI was seen in 85 patients (4.2%). After adjustment for potential confounding risk factors, patients with proteinuria had a fivefold higher risk of CI-AKI than patients without proteinuria (OR=5.74; 95% CI 2.23 to 14.83; p<0.001). Other independent risk factors for CI-AKI were estimated glomerular filtration rate <60 mL/min/1.73 m
conclusionsProteinuria is an independent risk factor for CI-AKI and 1-year mortality in patients with stroke undergoing cerebral angiography. More attention should be paid to the development of CI-AKI in patients with stroke with proteinuria.
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