Evidence map›Paper›PMID 27106390›Full record

ReviewJournal of infection and public health

MERS-CoV diagnosis: An update.

Sameera Al Johani, Ali H Hajeer

Open access · greenAbstract readReview
In one paragraph

Review in Journal of infection and public health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 72 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Development of gold nanoparticle-based biosensors for COVID-19 diagnosis.Beni-Suef University journal of basic and applied sciences · 2022
    Review
  6. Article
  7. Article
  8. Review
  9. COVID-19 clinical and laboratory diagnosis overview.The Journal of the Egyptian Public Health Association · 2021
    Review
  10. Nucleic Acid Testing of SARS-CoV-2.International journal of molecular sciences · 2021
    Review
  11. Review
  12. Considerations for diagnostic COVID-19 tests.Nature reviews. Microbiology · 2021
    Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Review
  19. Review
  20. Diagnostic value and dynamic variance of serum antibody in coronavirus disease 2019.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sameera Al JohaniDepartment of Pathology and Laboratory Medicine, King Saud University for Health Sciences, Riyadh, Saudi Arabia. Electronic address: johanis@ngha.med.sa.
Ali H HajeerDepartment of Pathology and Laboratory Medicine, King Saud University for Health Sciences, Riyadh, Saudi Arabia.
King Saud University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diagnosis of MERS-Cov still a major concern in most of daignostic laboratories. To date the Real-time Polymerase Chain reaction (RT-PCR) is the mainstay for diagnosis of MERS-CoV. RT-PCR has limitations, including a long turnaround time and lack of common measurements and correlations with Viral Load (VL). It is recommended to screen for MERS-CoV using RT-PCR of the upstream of envelope gene (upE) followed by confirmation of the presence of one of the following genes; open reading frame 1A, 1B genes or nucleocapsid (N) gene. Scientists are looking to implement viral sequencing on all negative samples by RT-PCR and they beleive that can be exposed to another level of testing using sequencing of the RNA-dependent RNA polymerase (RdRp) gene or N gene and in this case a positive result is diagnostic. It is also very important to maintain a contineous and random sequencing for MERS-Cov samples to be able to pick early viral mutations. Serological assays still not widely or routinely performed, and a lot of studies looking to implement such method in routine patient's testings.

Indexed as

Coronavirus InfectionsHumansMiddle East Respiratory Syndrome CoronavirusMolecular Diagnostic TechniquesReal-Time Polymerase Chain ReactionSequence Analysis, DNASerologic TestsMERS-COVRT-PCRSequencingSerology

Identifiers

PMID27106390
PMCPMC7102781
OpenAlexW2337623699

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.