SynthesisPloS one2016
Can We Identify the Active Ingredients of Behaviour Change Interventions for Coronary Heart Disease Patients? A Systematic Review and Meta-Analysis.
Synthesis in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 99 citations in OpenAlex.
- Advancing translational research in digital cardiac rehabilitation: The preparation phase of the Multiphase Optimization Strategy.Translational behavioral medicine · 2025Pooled it
- The effectiveness of app-based mobile interventions on nutrition behaviours and nutrition-related health outcomes: A systematic review and meta-analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2019Pooled it
- Impact of clinical pharmacist-led behavioural theory-based discharge service to promote medication adherence in patients with acute coronary syndrome: a randomised controlled trial.International journal of clinical pharmacy · 2026Trial
- Optimizing Digital Cardiac Rehabilitation Using the Multiphase Optimization Strategy: Mixed Methods Feasibility Study.JMIR formative research · 2026Trial
- Short-term outcome of personalized theory-based pharmaceutical care service on the medication administration problems of family caregivers: a pre-post intervention study.International journal of clinical pharmacy · 2025Article
- Behavior change theory and behavior change technique use in cancer rehabilitation interventions: a secondary analysis.European journal of physical and rehabilitation medicine · 2024Article
- Persuasive Systems Design Trends in Coronary Heart Disease Management: Scoping Review of Randomized Controlled Trials.JMIR cardio · 2024Article
- Personalised exercise therapy and self-management support for people with multimorbidity: Development of the MOBILIZE intervention.Pilot and feasibility studies · 2022Article
- Key process features of personalized diet counselling in metabolic syndrome: secondary analysis of feasibility study in primary care.BMC nutrition · 2022Article
- Cardiac Rehabilitation in German Speaking Countries of Europe-Evidence-Based Guidelines from Germany, Austria and Switzerland LLKardReha-DACH-Part 2.Journal of clinical medicine · 2021Review
- Are behaviour change techniques and intervention features associated with effectiveness of digital cardiac rehabilitation programmes? A systematic review protocol.HRB open research · 2021Article
- Health behaviour change in cardiovascular disease prevention and management: meta-review of behaviour change techniques to affect self-regulation.Health psychology review · 2020Article
- Self-regulation mechanisms in health behavior change: a systematic meta-review of meta-analyses, 2006-2017.Health psychology review · 2020Article
- Examining overlap of included studies in meta-reviews: Guidance for using the corrected covered area index.Research synthesis methods · 2020Article
- Clinical Practice Guideline for Cardiac Rehabilitation in Korea: Recommendations for Cardiac Rehabilitation and Secondary Prevention after Acute Coronary Syndrome.Korean circulation journal · 2019Review
- Clinical Practice Guideline for Cardiac Rehabilitation in Korea.The Korean journal of thoracic and cardiovascular surgery · 2019Article
- Clinical Practice Guideline for Cardiac Rehabilitation in Korea.Annals of rehabilitation medicine · 2019Article
- DEBATE: Do interventions based on behavioral theory work in the real world?The international journal of behavioral nutrition and physical activity · 2019Article
- Electronic Health Physical Activity Behavior Change Intervention to Self-Manage Cardiovascular Disease: Qualitative Exploration of Patient and Health Professional Requirements.Journal of medical Internet research · 2018Article
- Effective Dementia Education and Training for the Health and Social Care Workforce: A Systematic Review of the Literature.Review of educational research · 2017Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe main behaviour change intervention available for coronary heart disease (CHD) patients is cardiac rehabilitation. There is little recognition of what the active ingredients of behavioural interventions for CHD might be. Using a behaviour change technique (BCT) framework to code existing interventions may help to identify this. The objectives of this systematic review are to determine the effectiveness of CHD behaviour change interventions and how this may be explained by BCT content and structure. METHODS AND
findingsA systematic search of Medline, EMBASE and PsycInfo electronic databases was conducted over a twelve year period (2003-2015) to identify studies which reported on behaviour change interventions for CHD patients. The content of the behaviour change interventions was coded using the Coventry Aberdeen and London-Refined (CALO-RE) taxonomy. Meta-regression analyses examined the BCT content as a predictor of mortality. Twenty two papers met the criteria for this review, reporting data on 16,766 participants. The most commonly included BCTs were providing information, and goal setting. There was a small but significant effect of the interventions on smoking (risk ratio (RR) = 0.89, 95% CI 0.81-0.97). The interventions did not reduce the risk of CHD events (RR = 0.86, 95% CI 0.68, 1.09), but significantly reduced the risk of mortality (RR = 0.82, 95% CI 0.69, 0.97). Sensitivity analyses did not find that any of the BCT variables predicted mortality and the number of BCTs included in an intervention was not associated with mortality (β = -0.02, 95% CI -0.06-0.03).
conclusionsBehaviour change interventions for CHD patients appear to have a positive impact on a number of outcomes. Using an existing BCT taxonomy to code the interventions helped us to understand which were the most commonly used techniques, providing information and goal setting, but not the active components of these complex interventions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.